PRKAB1

Gene Symbol	PRKAB1
Entrez Gene	5564
Alt Symbol	AMPK, HAMPKb
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, beta 1 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase beta-1 subunit|5'-AMP-activated protein kinase subunit beta-1|AMP-activated protein kinase beta subunit|AMPK beta -1 chain|AMPK beta 1|AMPK subunit beta-1|AMPKb|protein kinase, AMP-activated, noncatalytic, beta-1
Swissprots	Q9Y478 Q9UE20 Q9UEX2 Q9Y6V8 Q9UBV0
Accessions	AAB71326 AAD00625 EAW98151 EAW98152 EAW98153 EAW98154 Q9Y478 AF022116 AAC98897 AJ224515 CAA12024 AK127820 AK301165 BAG62754 AK312495 BAG35397 BC001007 AAH01007 BC001056 AAH01056 BC001823 AAH01823 BC017671 AAH17671 BC018818 BU539177 BX537486 U83994 AAD09237 Y12556 CAA73146 XM_005253909 XP_005253966 NM_006253 NP_006244
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AMPKa Total and Phospho T172 In-Cell ELISA Kit (IR) - ab151280 from Abcam Category ELISA Kit Prices $438.00 Sizes 1 x 96 tests Range 12000 cells/well - 100000 cells/well

Human PRKAB1 / AMPK Beta 1 ELISA Kit (Sandwich ELISA) - LS-F5051 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 0.156-10 ng/ml

Rat PRKAB1 / AMPK Beta 1 ELISA Kit (Sandwich ELISA) - LS-F4899 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.057 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-PRKAB1 / AMPK Beta 1 (Ser181) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1118 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat PRKAB1 / AMPK Beta 1 ELISA Kit (Cell-Based ELISA) - LS-F1793 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human PRKAB1 / AMPK Beta 1 ELISA Kit (Sandwich ELISA) - LS-F10704 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 0.156-10 ng/ml

Rat PRKAB1 / AMPK Beta 1 ELISA Kit (Sandwich ELISA) - LS-F10703 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human PRKAb1 ELISA Kit - abx152823 from Abbexa Category ELISA Kit Sensitivity 0.124 ng/ml Range 0.313 ng/ml - 20 ng/ml

5'-AMP-activated protein kinase subunit beta-1, PRKAB1, Human, ELISA Kit - E1671h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

PRKAB1 (Human) Matched Antibody Pair - H00005564-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

AMPK beta1 Colorimetric Cell-Based ELISA Kit - CB5035 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

AMPK beta1 (Phospho-Ser181) Colorimetric Cell-Based ELISA Kit - CBP1102 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Protein Kinase, AMP Activated Beta 1 (PRKAb1), ELISA Kit - MBS9311053 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Protein Kinase, AMP Activated Beta 1 (PRKAb1) - SEB671Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.124ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Protein Kinase, AMP Activated Beta 1 (PRKAb1) - SEB671Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.057ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Mouse PRKAB1 / AMPK Beta 1 ELISA Kit (Custom ELISA) - LS-F18277 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Pig PRKAB1 / AMPK Beta 1 ELISA Kit (Custom ELISA) - LS-F18278 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Bovine PRKAB1 / AMPK Beta 1 ELISA Kit (Custom ELISA) - LS-F18279 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

5'-AMP-activated protein kinase subunit beta-1, ELISA Kit - MBS288341 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.78 ng/ml -50.0 ng/ml.

5'-AMP-activated protein kinase subunit beta-1, ELISA Kit - MBS288150 from MyBioSource Category ELISA Kit Prices $430.00, $570.00, $2,515.00, $4,520.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Protein Kinase,AMP Activated Beta 1 (PRKAb1), Human, ELISA Kit - DL-PRKAb1-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human PRKAb1 ELISA Kit - abx572166 from Abbexa Category ELISA Kit Sensitivity 0.124 ng/ml Range 0.313 ng/ml - 20 ng/ml

PRKAB1 - EKH3762 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

PRKAB1 ELISA Kit (Human) (OKEH01208) - OKEH01208 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.16 ng/mL Range 0.312 - 20 ng/mL

Human PRKAB1 ELISA Kit - E031653 from Biobool Category ELISA Kit Sensitivity Typically less than 0.124ng/mL.

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