PRKAB1

Gene Symbol	PRKAB1
Entrez Gene	5564
Alt Symbol	AMPK, HAMPKb
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, beta 1 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase beta-1 subunit|5'-AMP-activated protein kinase subunit beta-1|AMP-activated protein kinase beta subunit|AMPK beta -1 chain|AMPK beta 1|AMPK subunit beta-1|AMPKb|protein kinase, AMP-activated, noncatalytic, beta-1
Swissprots	Q9Y478 Q9UE20 Q9UEX2 Q9Y6V8 Q9UBV0
Accessions	AAB71326 AAD00625 EAW98151 EAW98152 EAW98153 EAW98154 Q9Y478 AF022116 AAC98897 AJ224515 CAA12024 AK127820 AK301165 BAG62754 AK312495 BAG35397 BC001007 AAH01007 BC001056 AAH01056 BC001823 AAH01823 BC017671 AAH17671 BC018818 BU539177 BX537486 U83994 AAD09237 Y12556 CAA73146 XM_005253909 XP_005253966 NM_006253 NP_006244
Function	Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AMPKβ1 siRNA (h) - sc-38925 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AMPKβ1 shRNA Plasmid (h) - sc-38925-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AMPKβ1 shRNA (h) Lentiviral Particles - sc-38925-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AMPK beta 1 RNAi - H00005564-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU035991 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK1783 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1784 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1782 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN1142 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1142 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08791 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr08791

PRKAB1 siRNA (Human) - CRH3736 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human PRKAB1 (NM_006253.4) - SHH382648 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PRKAB1(NM_006253.4) - SHR139224 from Creative biogene Category siRNA Species Reactivities Human

Human PRKAB1 siRNA - orb264238 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PRKAB1 shRNA Plasmid (Human) - CHH3736 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PRKAB1 miRNA 3'UTR clone - MiUTR3H-05279 from Creative biogene Species Reactivities Human

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