DDIT3

Gene Symbol DDIT3
Entrez Gene 1649
Alt Symbol CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Species Human
Gene Type protein-coding
Description DNA-damage-inducible transcript 3
Other Description C/EBP zeta|CCAAT/enhancer-binding protein homologous protein|DDIT-3|DNA damage-inducible transcript 3 protein|c/EBP-homologous protein 10|growth arrest and DNA damage-inducible protein GADD153
Swissprots F8VS99 P35638
Accessions AAW56077 EAW97021 EAW97022 EAW97023 P35638 AA054097 AA476561 AI658803 AK316581 BAG38169 AV729744 AY461580 BC003637 AAH03637 BC064556 BC107859 BM464290 BT006691 AAP35337 BU664077 CN482428 EU831488 ACE87175 EU831575 ACE86494 S40706 AAB22646 XM_011538006 XP_011536308 NM_001195053 NP_001181982 NM_001195054 NP_001181983 NM_001195055 NP_001181984 NM_001195056 NP_001181985 NM_001195057 NP_001181986 NM_004083 NP_004074
Function Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the c
Subcellular Location Cytoplasm. Nucleus. Note=Present in the cytoplasm under non-stressed conditions and ER stress leads to its nuclear accumulation.
Top Pathways MAPK signaling pathway, Protein processing in endoplasmic reticulum, Non-alcoholic fatty liver disease (NAFLD), Transcriptional misregulation in cancer

Mouse/Human/Rat DDIT3 / CHOP ELISA Kit (Cell-Based ELISA) - LS-F2986 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 0.313-20 ng/ml

Human DDIT3 / CHOP ELISA Kit (Sandwich ELISA) - LS-F8872 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 0.114 ng/ml
Range 0.313-20 ng/ml

Mouse DDIT3 / CHOP ELISA Kit (Sandwich ELISA) - LS-F9101 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 0.054 ng/ml
Range 0.313-20 ng/ml

Human DDIT3 / CHOP ELISA Kit (Sandwich ELISA) - LS-F11284 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.78
Range 0.313-20 ng/ml

Rat DDIT3 / CHOP ELISA Kit (Sandwich ELISA) - LS-F11285 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.313-20 ng/ml

Human DDIT3 ELISA Kit - abx151267 from Abbexa

Category ELISA Kit
Sensitivity 0.138 ng/ml
Range 0.313 ng/ml - 20 ng/ml

CCAAT/enhancer-binding protein zeta (CEBPZ), Human, ELISA Kit - E01C1607 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

DNA Damage Inducible Transcript 3 (DDIT3), Human, ELISA Kit - SEJ282Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.138ng/mL
Range 0.312-20ng/mL

DNA damage-inducible transcript 3 protein, DDIT3, Human, ELISA Kit - E9115h from ARP American Research Products

Category ELISA Kit
Prices $660.00
Sizes 96 t
Range 0.78-50 ng/mL

Fusion (FUS), Human, ELISA Kit - SEC260Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 0.057ng/mL
Range 0.156-10ng/mL

GADD153 Colorimetric Cell-Based ELISA - CB5748 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

DNA Damage Inducible Transcript 3, ELISA Kit - MBS755202 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS024071 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS069906 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA Damage Inducible Transcript 3, ELISA Kit - MBS752922 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS010785 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1ng/ml.
Range 0.25ng/ml-8ng/ml.

Dna Damage Inducible Transcript 3, ELISA Kit - MBS098599 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA Damage Inducible Transcript 3, ELISA Kit - MBS750900 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS008758 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS022840 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS042304 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

DNA Damage Inducible Transcript 3, ELISA Kit - MBS744516 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS009801 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS035659 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Dna Damage Inducible Transcript 3, ELISA Kit - MBS082768 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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