CYP4F11

Gene Symbol CYP4F11
Entrez Gene 57834
Alt Symbol CYPIVF11
Species Human
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily F, polypeptide 11
Other Description 3-hydroxy fatty acids omega-hydroxylase CYP4F11|cytochrome P450 4F11|cytochrome P450, subfamily IVF, polypeptide 11|phylloquinone omega-hydroxylase CYP4F11
Swissprots Q96AQ5 A8K059 A0A024R7G0 Q9HBI6 O75254
Accessions AAC27731 EAW84511 EAW84512 EAW84513 EAW84514 EAW84515 Q9HBI6 AF236085 AAG15889 AK125714 AK289424 BAF82113 AK309292 AL833940 CAD38795 BC016853 AAH16853 BM727421 BU180723 DC345817 DQ891467 ABM82393 DQ894650 ABM85576 XM_011528156 XP_011526458 NM_001128932 NP_001122404 NM_021187 NP_067010
Function Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545). {ECO:0000269|PubMed:15364545, ECO:0000269|PubMed:18065749, ECO:0000269|PubMed:19932081, ECO:0000269|PubMed:24138531}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:18065749}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:10964514, ECO:0000269|PubMed:24138531}.

CYP4F11-Over-expression-Lysate - LY11661a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CYP4F11 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CYP4F11 gene

CYP4F11 293T Cell Transient Overexpression Lysate(Denatured) - H00057834-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CYP4F11 overexpression lysate - LY412026 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CYP4F11 overexpression lysate - LY427033 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CYP4F11 293 Cell Lysate - 405973 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Cytochrome P450 4F11 Overexpression Lysate (Denatured) - H00057834-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: CYP4F11 transfected lysate (57.75 KDa) Lane 2: Non-transfected lysate.

Cytochrome P450 4F11 Overexpression Lysate (Native) - NBL1-09697 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cytochrome P450 4F11 Overexpression Lysate (Adult Normal) [NBL1-09697] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytochrome P450 4F11.

CYP4F11 (h): 293T Lysate - sc-112784 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CYP4F11 (h2): 293T Lysate - sc-175635 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

CYP4F11 Over-expression Lysate Product - GWB-73ADED from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Cytochrome P450 4F11 Overexpression Lysate (Native) - NBP2-11110 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cytochrome P450 4F11 Overexpression Lysate (Adult Normal) [NBP2-11110] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytochrome P450 4F11.

Panoply™ Human CYP4F11 Knockdown Stable Cell Line - CSC-DC003978 from Creative biogene

Category Cell Line
Species Human
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