CYP4F11

Gene Symbol CYP4F11
Entrez Gene 57834
Alt Symbol CYPIVF11
Species Human
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily F, polypeptide 11
Other Description 3-hydroxy fatty acids omega-hydroxylase CYP4F11|cytochrome P450 4F11|cytochrome P450, subfamily IVF, polypeptide 11|phylloquinone omega-hydroxylase CYP4F11
Swissprots Q96AQ5 A8K059 A0A024R7G0 Q9HBI6 O75254
Accessions AAC27731 EAW84511 EAW84512 EAW84513 EAW84514 EAW84515 Q9HBI6 AF236085 AAG15889 AK125714 AK289424 BAF82113 AK309292 AL833940 CAD38795 BC016853 AAH16853 BM727421 BU180723 DC345817 DQ891467 ABM82393 DQ894650 ABM85576 XM_011528156 XP_011526458 NM_001128932 NP_001122404 NM_021187 NP_067010
Function Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545). {ECO:0000269|PubMed:15364545, ECO:0000269|PubMed:18065749, ECO:0000269|PubMed:19932081, ECO:0000269|PubMed:24138531}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:18065749}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:10964514, ECO:0000269|PubMed:24138531}.

CYP4F11 (F21 P6 F5) - sc-53619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP4F11 (F21 P6 F5): sc-53619. Western blot analysis of CYP4F11 expression in non-transfected: sc-117752 (A) and human CYP4F11 transfected: sc-112784 (B) 293T whole cell lysates.

Anti-CYPIVF11 antibody - ab126066 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CYPIVF11 antibody (ab126066) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg/ml

Anti-CYPIVF11 antibody - ab136114 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CYPIVF11 antibody (ab136114) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-CYPIVF11 antibody - ab172693 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-CYPIVF11 antibody (ab172693) at 1/500 dilutionLane 1 : CYPIVF11-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-CYPIVF11 antibody [F21 P6 F5] - ab55841 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone F21 P6 F5
All lanes : Anti-CYPIVF11 antibody [F21 P6 F5] (ab55841) at 1 µg/mlLane 1 : molecular weight markersLane 2 : normal kidney cell lysateLane 3 : kidney cancer cell lysateLysates/proteins at 20 µg per lane.

Anti-CYP4F11 Antibody - LS-C27027 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
A. IHC of human liposarcoma cells using CYP4F11 antibody (LS-C27027). B. Western blot of CYP4F11 antibody one normal (2) and cancerous (3) kidney cell lysates.

Anti-CYP4F11 Antibody (aa51-100) - LS-C31906 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
HepG2 Cell Lysate

Anti-CYP4F11 Antibody - LS-C155466 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: HepG2 7.5% SDS PAGE CYP4F11 / CYPIVF11 antibody diluted at 1:1000

Anti-CYP4F11 Antibody (aa325-374) - LS-C291862 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Cytochrome P450 4F11 Antibody - NBP1-87461 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cytochrome P450 4F11 Antibody - NBP2-16082 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome P450 4F11 Antibody [NBP2-16082] - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000.

Cytochrome P450 4F11 Antibody - NBP1-69423 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Cytochrome P450 4F11 Antibody [NBP1-69423] - This Anti-CYP4F11 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 5ug/ml.

Cytochrome P450 4F11 Antibody - H00057834-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Cytochrome P450 4F11 Antibody [H00057834-B01] - analysis of CYP4F11 expression in transfected 293T cell line by CYP4F11 MaxPab polyclonal antibody (B01). Lane 1: CYP4F11 transfected lysate (60.20 KDa). Lane 2: Non-transfected lysate.

Anti-CYP4F11 antibody produced in rabbit - HPA017265 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CYP4F11: <B>Cat. No. HPA017265</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human stomach shows strong cytoplamsic and membranous positivity in glandular cells.

Anti-CYP4F11 antibody produced in rabbit - AV42588 from Sigma-Aldrich

Prices $242.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV42588</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 5.0 μg/mL in cell type HepG2

Monoclonal Anti-Cytochrome P450 4F11 antibody produced in mouse - C4868 from Sigma-Aldrich

Prices $389.50
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone F21P6F5
<B>Immunoblotting</B><BR/>Recombinant Cytochrome P450 4F11 protein was separated on SDS-PAGE and blotted with Monoclonal Anti-Cytochrome P450 4F11 (<B>Cat. No. C4868</B>). The antibody was developed with Goat Anti-Mouse IgG, Peroxidase conjugate (<B>Cat. No. A2304</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1: 10 μg/mL antibody<BR/>2: 3 μg/mL antibody<BR/>3: 1 μg/mL antibody<BR/>4: 0.3 μg/mL antibody<BR/>5: 0.1 μg/mL antibody

CYP4F11 antibody - N-terminal region (ARP42588_T100) - ARP42588_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Cytochrome P450 4F11 antibody [N1N3] - GTX116701 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-CYP4F11 antibody [N1N3] used in Western blot. GTX116701

CYP4F11 Antibody (OAAF04610) - OAAF04610 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Cytochrome P450 4F11 Antibody (OAAF06291) - OAAF06291 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CYP4F11 antibody - 70R-1872 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CYP4F11 antibody - 70R-16721 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti -CYP4F11 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 11, CYPIVF11) - 210385 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -Cytochrome P450 4F11 (CYP4F11) - 217899 from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone F21 P6 F5

CYP4F11 Polyclonal Antibody - A4900 from ABclonal

Prices $200.00, $480.00
Sizes 50 µg, 200 µg
Host Rabbit
Clonality Polyclonal
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