CYP4F11

Gene Symbol	CYP4F11
Entrez Gene	57834
Alt Symbol	CYPIVF11
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 4, subfamily F, polypeptide 11
Other Description	3-hydroxy fatty acids omega-hydroxylase CYP4F11|cytochrome P450 4F11|cytochrome P450, subfamily IVF, polypeptide 11|phylloquinone omega-hydroxylase CYP4F11
Swissprots	Q96AQ5 A8K059 A0A024R7G0 Q9HBI6 O75254
Accessions	AAC27731 EAW84511 EAW84512 EAW84513 EAW84514 EAW84515 Q9HBI6 AF236085 AAG15889 AK125714 AK289424 BAF82113 AK309292 AL833940 CAD38795 BC016853 AAH16853 BM727421 BU180723 DC345817 DQ891467 ABM82393 DQ894650 ABM85576 XM_011528156 XP_011526458 NM_001128932 NP_001122404 NM_021187 NP_067010
Function	Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545). {ECO:0000269|PubMed:15364545, ECO:0000269|PubMed:18065749, ECO:0000269|PubMed:19932081, ECO:0000269|PubMed:24138531}.
Subcellular Location	Microsome membrane {ECO:0000269|PubMed:18065749}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity	Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:10964514, ECO:0000269|PubMed:24138531}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYPIVF11 full length protein - ab163663 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human Cytochrome P450 4F11 Protein - H00057834-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Human CYP4F11 protein - orb246640 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

CYP4F11 Blocking Peptide - 33R-3022 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CYP4F11 - H00057834-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CYP4F11 - H00057834-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CYP4F11 fusion protein - ag2906 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CYP4F11, GST-tagged - CYP4F11-11789H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant human Cytochrome P450 4F11 - CSB-YP872539HU CSB-BP872539HU CSB-MP872539HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Cytochrome P450 4F11 - CSB-EP872539HU from Cusabio Category Protein Source E.coli Species Human

CYP4F11 (transcript variant 1) - TP303705 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

CYP4F11 (transcript variant 2) - TP325897 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Cytochrome P450 4F11 Recombinant Protein Antigen - NBP1-87461PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CYP4F11-Antibody-N-term-Blocking-Peptide - BP9058a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP4F11 Peptide, Human - M34GP03978H from Creative Peptides Category Peptide Source Synthetic. Species Human

CYP4F11 Recombinant Protein (OPCA02490) - OPCA02490 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant human Cytochrome P450 4F11 - AP71555 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E.coli Species Human

Cytochrome P450 4F11, Recombinant Protein - MBS969752 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Cytochrome P450 4F11, Recombinant Protein - MBS9421417 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source E Coli Species Human

Cytochrome P450 4F11 (CYP4F11), Recombinant Protein - MBS7013457 from MyBioSource Category Protein Prices $1,320.00, $2,310.00, $3,515.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Recombinant Human Cytochrome P450 4F11 (CYP4F11) - RPC23610 from Biomatik Category Protein Prices $187.00, $342.00, $1,692.00 Sizes 50 µg, 100 µg, 1 mg Source E.coli Species Human

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