CYP4F11

Gene Symbol CYP4F11
Entrez Gene 57834
Alt Symbol CYPIVF11
Species Human
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily F, polypeptide 11
Other Description 3-hydroxy fatty acids omega-hydroxylase CYP4F11|cytochrome P450 4F11|cytochrome P450, subfamily IVF, polypeptide 11|phylloquinone omega-hydroxylase CYP4F11
Swissprots Q96AQ5 A8K059 A0A024R7G0 Q9HBI6 O75254
Accessions AAC27731 EAW84511 EAW84512 EAW84513 EAW84514 EAW84515 Q9HBI6 AF236085 AAG15889 AK125714 AK289424 BAF82113 AK309292 AL833940 CAD38795 BC016853 AAH16853 BM727421 BU180723 DC345817 DQ891467 ABM82393 DQ894650 ABM85576 XM_011528156 XP_011526458 NM_001128932 NP_001122404 NM_021187 NP_067010
Function Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:24138531). Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3- hydroxyarachidonate, and 3-hydroxystearate (PubMed:18065749, PubMed:19932081). Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine (PubMed:15364545). {ECO:0000269|PubMed:15364545, ECO:0000269|PubMed:18065749, ECO:0000269|PubMed:19932081, ECO:0000269|PubMed:24138531}.
Subcellular Location Microsome membrane {ECO:0000269|PubMed:18065749}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed mainly in human liver, followed by kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:10964514, ECO:0000269|PubMed:24138531}.

CYP4F11 CRISPR/Cas9 KO Plasmid (h) - sc-405267 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 HDR Plasmid (h) - sc-405267-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 Double Nickase Plasmid (h) - sc-405267-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 Double Nickase Plasmid (h2) - sc-405267-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 CRISPR Activation Plasmid (h) - sc-405267-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 CRISPR Activation Plasmid (h2) - sc-405267-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 Lentiviral Activation Particles (h) - sc-405267-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 Lentiviral Activation Particles (h2) - sc-405267-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CYP4F11 siRNA (h) - sc-63345 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP4F11 shRNA Plasmid (h) - sc-63345-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CYP4F11 shRNA (h) Lentiviral Particles - sc-63345-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytochrome P450 4F11 RNAi - H00057834-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU148111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2474 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2474 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CYP4F11 siRNA (Human) - CRJ1695 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYP4F11 - MBS8203124 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYP4F11 (NM_021187.3) - SHH273641 from Creative biogene

Category siRNA
Species Reactivities Human

CYP4F11 shRNA Plasmid (Human) - CHJ1695 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYP4F11 miRNA 3'UTR clone - MiUTR3H-11949 from Creative biogene

Species Reactivities Human

CYP4F11 miRNA 3'UTR clone - MiUTR3H-11950 from Creative biogene

Species Reactivities Human
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