MCMBP

Gene Symbol MCMBP
Entrez Gene 79892
Alt Symbol C10orf119, MCM-BP
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex binding protein
Other Description MCM-binding protein|mini-chromosome maintenance complex-binding protein|minichromosome maintenance complex-binding protein
Swissprots Q9H916 Q9BTE3 Q9BVT9 B3KSP7 Q6IA56
Accessions EAW49375 EAW49376 EAW49377 EAW49378 Q9BTE3 AA292620 AK001928 AK023143 BAB14427 AK094075 BAG52809 BC000935 AAH00935 BC004183 AAH04183 BC007219 AAH07219 BQ929053 CN259319 CR457299 CAG33580 DA381502 XM_005270157 XP_005270214 XM_011540170 XP_011538472 NM_001256378 NP_001243307 NM_001256379 NP_001243308 NM_024834 NP_079110
Function Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. {ECO:0000269|PubMed:20090939, ECO:0000269|PubMed:21196493}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17296731}. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.

MCM-BP (E-19) - sc-243441 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MCM-BP antibody - ab122478 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122478 at 1/50 dilution staining MCM-BP in paraffin-embedded Human stomach tissue by Immunohistochemistry.

Anti-MCM-BP antibody - ab183142 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling MCM-BP with ab183142 at 1/60 dilution.The sample on the right is treated with the synthetic peptide.

Anti-MCM-BP antibody - ab124290 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MCM-BP antibody (ab124290) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL techniqueExposure time : 3 minutes

Anti-MCMBP / C10orf119 Antibody (aa150-179, AP) - LS-C233870 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179, Biotin) - LS-C233872 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179, APC) - LS-C233871 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179, FITC) - LS-C233874 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179, PE) - LS-C233878 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179, Azide-free, HRP) - LS-C249681 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa150-179) - LS-C320406 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP / C10orf119 Antibody (aa158-207) - LS-C187100 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of 721_B. METTL21C antibody dilution 1.0 ug/ml.

Anti-MCMBP / C10orf119 Antibody (aa150-200) - LS-C290151 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human MCM-BP by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-MCM-BP antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B).

Anti-MCMBP / C10orf119 Antibody (aa143-171) - LS-C168791 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CJ119 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cervix carcinoma tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

MCMBP Antibody - NBP1-90746 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MCMBP Antibody [NBP1-90746] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

ANTI-CJ119 (N-TERM) antibody produced in rabbit - SAB1302974 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>CJ119 (N-term): <B>Cat. No. SAB1302974</B>: CJ119 in Human cervix carcinoma. tissue with CJ119 antibody (N-term) at 5 μg/mL.

Anti-MCMBP antibody produced in rabbit - SAB4300880 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MCMBP antibody produced in rabbit - HPA038481 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MCMBP: <B>Cat. No. HPA038481</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

MCMBP Antibody - N-terminal region (ARP70846_P050) - ARP70846_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C10orf119 Antibody - N-terminal region (OAAB02148) - OAAB02148 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

CJ119-Antibody-N-term - AP4727a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of CJ119 Antibody (N-term) (Cat. #AP4727a) in MDA-MB231 cell line lysates (35ug/lane). CJ119 (arrow) was detected using the purified Pab.

MCMBP antibody - GTX120103 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-C10orf119 antibody used in Western blot. GTX120103

MCMBP antibody - GTX53670 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-MCMBP antibody used in Western blot. GTX53670

C10orf119 antibody - 70R-16053 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti -CJ119, NT (MCMBP, C10orf119, Mini-chromosome maintenance complex-binding protein) - 033923 from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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