MCMBP

Gene Symbol MCMBP
Entrez Gene 79892
Alt Symbol C10orf119, MCM-BP
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex binding protein
Other Description MCM-binding protein|mini-chromosome maintenance complex-binding protein|minichromosome maintenance complex-binding protein
Swissprots Q9H916 Q9BTE3 Q9BVT9 B3KSP7 Q6IA56
Accessions EAW49375 EAW49376 EAW49377 EAW49378 Q9BTE3 AA292620 AK001928 AK023143 BAB14427 AK094075 BAG52809 BC000935 AAH00935 BC004183 AAH04183 BC007219 AAH07219 BQ929053 CN259319 CR457299 CAG33580 DA381502 XM_005270157 XP_005270214 XM_011540170 XP_011538472 NM_001256378 NP_001243307 NM_001256379 NP_001243308 NM_024834 NP_079110
Function Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. {ECO:0000269|PubMed:20090939, ECO:0000269|PubMed:21196493}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17296731}. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.

MCM-BP CRISPR/Cas9 KO Plasmid (h) - sc-417931 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP HDR Plasmid (h) - sc-417931-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP Double Nickase Plasmid (h) - sc-417931-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP Double Nickase Plasmid (h2) - sc-417931-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP CRISPR Activation Plasmid (h) - sc-417931-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP CRISPR Activation Plasmid (h2) - sc-417931-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP Lentiviral Activation Particles (h) - sc-417931-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP Lentiviral Activation Particles (h2) - sc-417931-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MCM-BP siRNA (h) - sc-90695 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM-BP shRNA Plasmid (h) - sc-90695-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MCM-BP shRNA (h) Lentiviral Particles - sc-90695-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU122861 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN13127 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13127 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10917 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10917

MCMBP siRNA (Human) - CRJ2646 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MCMBP (NM_024834.3) - SHH339379 from Creative biogene

Category siRNA
Species Reactivities Human

MCMBP shRNA Plasmid (Human) - CHJ2646 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MCMBP miRNA 3'UTR clone - MiUTR4H-TG01264 from Creative biogene

Species Reactivities Human
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