MCMBP

Gene Symbol	MCMBP
Entrez Gene	79892
Alt Symbol	C10orf119, MCM-BP
Species	Human
Gene Type	protein-coding
Description	minichromosome maintenance complex binding protein
Other Description	MCM-binding protein|mini-chromosome maintenance complex-binding protein|minichromosome maintenance complex-binding protein
Swissprots	Q9H916 Q9BTE3 Q9BVT9 B3KSP7 Q6IA56
Accessions	EAW49375 EAW49376 EAW49377 EAW49378 Q9BTE3 AA292620 AK001928 AK023143 BAB14427 AK094075 BAG52809 BC000935 AAH00935 BC004183 AAH04183 BC007219 AAH07219 BQ929053 CN259319 CR457299 CAG33580 DA381502 XM_005270157 XP_005270214 XM_011540170 XP_011538472 NM_001256378 NP_001243307 NM_001256379 NP_001243308 NM_024834 NP_079110
Function	Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. {ECO:0000269|PubMed:20090939, ECO:0000269|PubMed:21196493}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:17296731}. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MCMBP / C10orf119 Antibody Blocking Peptide - LS-E25097 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MCMBP / C10orf119 Antibody Blocking Peptide - LS-E7565 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CJ119-Antibody-N-term-Blocking-Peptide - BP4727a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

C10orf119 fusion protein - Ag13967 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

C10orf119 fusion protein - Ag14961 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

C10orf119 fusion protein - ag13750 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

C10orf119 fusion protein - ag14748 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human C10orf119, His-tagged - C10orf119-10347H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Mini-chromosome maintenance complex-binding protein(MCMBP) - CSB-YP880100HU CSB-EP880100HU CSB-BP880100HU CSB-MP880100HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MCMBP Peptide - abx164790 from Abbexa Category Peptide Species Human, Mouse, Rat

MCMBP Recombinant Protein Antigen - NBP1-90746PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

C10orf119 Antibody - SH-A10660 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

MCMBP Peptide, Human - M34GP09322H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mini-chromosome maintenance complex-binding protein (MCMBP), Recombinant Protein - MBS1298271 from MyBioSource Category Protein Prices $1,440.00, $1,440.00, $1,670.00, $1,670.00, $2,440.00, $2,440.00, $2,885.00, $2,885.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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