MCMBP

Gene Symbol MCMBP
Entrez Gene 79892
Alt Symbol C10orf119, MCM-BP
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex binding protein
Other Description MCM-binding protein|mini-chromosome maintenance complex-binding protein|minichromosome maintenance complex-binding protein
Swissprots Q9H916 Q9BTE3 Q9BVT9 B3KSP7 Q6IA56
Accessions EAW49375 EAW49376 EAW49377 EAW49378 Q9BTE3 AA292620 AK001928 AK023143 BAB14427 AK094075 BAG52809 BC000935 AAH00935 BC004183 AAH04183 BC007219 AAH07219 BQ929053 CN259319 CR457299 CAG33580 DA381502 XM_005270157 XP_005270214 XM_011540170 XP_011538472 NM_001256378 NP_001243307 NM_001256379 NP_001243308 NM_024834 NP_079110
Function Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. Required for sister chromatid cohesion. {ECO:0000269|PubMed:20090939, ECO:0000269|PubMed:21196493}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17296731}. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex.

chromosome 10 open reading frame 119, ELISA Kit - MBS9326413 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human C10orf119 ELISA Kit - E008539 from Biobool

Category ELISA Kit

Human MCMBP ELISA Kit - E089321 from Biobool

Category ELISA Kit

anti-MCM-BP antibody - ARG55091 from Arigo Biolaboratories

Category ELISA Kit
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