HSD3B1

Gene Symbol	HSD3B1
Entrez Gene	3283
Alt Symbol	3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1
Species	Human
Gene Type	protein-coding
Description	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Other Description	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1|3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I|3-beta-HSD I|3-beta-hydroxy-5-ene steroid dehydrogenase|3-beta-hydroxy-Delta(5)-steroid dehydrogenase|delta-5-3-ketosteroid isomerase|hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 1|progesterone reductase|short chain dehydrogenase/reductase family 11E, member 1|steroid Delta-isomerase|trophoblast antigen FDO161G
Swissprots	P14060 A8K691 Q8IV65 Q14545
Accessions	AAA36001 AAA51662 AAA51831 CBH19320 EAW56703 EAW56704 P14060 AK291556 BAF84245 AL544564 BC031999 AAH31999 DQ891161 ABM82087 DQ894342 ABM85268 M27137 AAA36015 M35493 AAA51538 S45679 AAB23543 X53321 CAA37408 X55997 CAA39469 XM_011541314 XP_011539616 NM_000862 NP_000853
Function	3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17- alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone. {ECO:0000269|PubMed:1401999, ECO:0000269|PubMed:2139411}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Tissue Specificity	Placenta and skin. Predominantly expressed in mammary gland tissue.
Top Pathways	Steroid hormone biosynthesis, Ovarian steroidogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, HSD3B1, Human, ELISA Kit - E2793h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.312-20 ng/mL

C-telopeptide of Collagen alpha-1(I) chain, CTXI, Human, ELISA Kit - E0665h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

C-terminal propeptide of Collagen alpha-1(I) chain, PICP, Human, ELISA Kit - E0570h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Cob (I)yrinic acid a, c-diamide adenosyltransferase, mitochondrial (MMAB), Human, ELISA Kit - E01C2339 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Cross-linked C-terminal telopeptide of Collagen alpha-1(I) chain, ICTP, Human, ELISA Kit - E0958h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

Cross-linked N-terminal telopeptide of Collagen alpha-1(I) chain, INTX, Human, ELISA Kit - E0639h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.47-30 ng/mL

N-terminal propeptide of Collagen alpha-1(I) chain, PINP, Human, ELISA Kit - E0957h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 3.12-200 ng/mL

HSD3B1 (Human) IP-WB Antibody Pair - H00003283-PW2 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

HSD3B1 (Human) Matched Antibody Pair - H00003283-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, ELISA Kit - MBS2602869 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse HSD3B1 ELISA Kit (Custom ELISA) - LS-F19793 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 ELISA Kit - abx251583 from Abbexa Category ELISA Kit Range 0.312 ng/ml - 20 ng/ml

Rat HSD3B1 ELISA Kit (Sandwich ELISA) - LS-F13037 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

Human 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 ELISA Kit - EKE53459 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.19 ng/mL Range 0.312-20 ng/mL

HSD3B1 - EKH4476 from Nordic BioSite Sensitivity 0.188ng/ml Range 0.312-20ng/ml

HSD3B1 ELISA Kit (Human) : 96 Wells (OKEH01670) - OKEH01670 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.19 ng/mL Range 0.312 - 20 ng/mL

Human HSD3B1 ELISA Kit - E041895 from Biobool Category ELISA Kit

Human 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 ELISA Kit - EK4545 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.098ng/mL Range 0.156-10 ng/mL

anti-HSD3B1 antibody - ARG63931 from Arigo Biolaboratories Category ELISA Kit

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1), ELISA Kit - MBS2610485 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1), ELISA Kit - MBS2610558 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, ELISA Kit - MBS2881133 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.31-20.0 ng/mL

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, ELISA Kit - MBS9428371 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.19ng/mL Range 0.312-20 ng/mL

Rat HSD3B1 ELISA Kit (Sandwich ELISA) - LS-F34148 from LifeSpan Bioscience Category ELISA Kit Sensitivity 46.9 Range 78-5000 pg/ml

Human HSD3B1 ELISA Kit (Competitive EIA) - LS-F39431 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.188 Range 78-5000 pg/ml

Search more