SP3

Gene Symbol	SP3
Entrez Gene	6670
Alt Symbol	SPR2
Species	Human
Gene Type	protein-coding
Description	Sp3 transcription factor
Other Description	GC-binding transcription factor Sp3|specificity protein 3|transcription factor Sp3
Swissprots	Q69B26 B4E2B7 A0AVL9 Q8TD56 Q8WWU4 Q02447 Q69B27 Q9BQR1
Accessions	AAM12875 AAP03059 EAX11152 EAX11153 EAX11154 EAX11155 Q02447 AA706229 AB209334 BAD92571 AJ310752 CAC34575 AJ430844 CAD23619 AK304199 BAG65079 AW204666 AW295583 AY070137 AAL58086 AY441957 AAR30505 AY441958 AAR30506 BC042945 AAH42945 BC126414 AAI26415 BC143928 AAI43929 BQ010796 BX648857 CR749323 CAH18178 HQ258632 ADR83384 M97191 AAA36630 X68560 CAA48562 NM_001017371 NP_001017371 NM_001172712 NP_001166183 NM_003111 NP_003102
Function	Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone- induction and house-keeping. {ECO:0000269|PubMed:10391891, ECO:0000269|PubMed:11812829, ECO:0000269|PubMed:12419227, ECO:0000269|PubMed:12837748, ECO:0000269|PubMed:15247228, ECO:0000269|PubMed:15494207, ECO:0000269|PubMed:15554904, ECO:0000269|PubMed:16781829, ECO:0000269|PubMed:17548428, ECO:0000269|PubMed:18187045, ECO:0000269|PubMed:18617891, ECO:0000269|PubMed:9278495}.
Subcellular Location	Nucleus. Nucleus, PML body. Note=Localizes to the nuclear periphery and in nuclear dots when sumoylated. Some localization in PML nuclear bodies.
Tissue Specificity	Ubiquitously expressed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Transcription factor Sp3 (SP3), Human, ELISA Kit - E01T0651 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Transcription factor Sp3 (SP3), ELISA Kit - MBS7218440 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

TransAM® Sp1/Sp3 - 40496 from ActiveMotif

SP3/4 TFact™ DNA-Binding ELISA - TFE-7143 from Assay Biotechnology Category ELISA Kit Prices $495.00, $990.00, $1,485.00 Sizes 1 kit, 2 kits, 3 kits

Transcription factor Sp3 (SP3), ELISA Kit - MBS7219027 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7213439 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7249288 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7207070 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7240629 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7200952 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7236025 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7235263 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7211970 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 (SP3), ELISA Kit - MBS7208923 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SP3/4 ELISA Kit - DEIA-XYA1668 from Creative Diagnostics Category ELISA Kit

Human SP3 ELISA Kit - E038849 from Biobool Category ELISA Kit

Transcription factor Sp3 (SP3), ELISA Kit - MBS2610523 from MyBioSource Category ELISA Kit Prices $300.00, $475.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2606030 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2607741 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3 , ELISA Kit - MBS2607717 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2603615 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2604980 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2607115 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2607843 from MyBioSource Category ELISA Kit Prices $315.00, $490.00, $1,825.00, $3,425.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transcription factor Sp3, ELISA Kit - MBS2607610 from MyBioSource Category ELISA Kit Prices $290.00, $450.00, $1,755.00, $3,150.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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