MMEL1

Gene Symbol	MMEL1
Entrez Gene	79258
Alt Symbol	MMEL2, NEP2, NEPII, NL1, NL2, SEP
Species	Human
Gene Type	protein-coding
Description	membrane metallo-endopeptidase-like 1
Other Description	NEP2(m)|membrane metallo-endopeptidase-like 2|neprilysin II|neprilysin-2|soluble secreted endopeptidase|zinc metallopeptidase
Swissprots	Q495T6 B9DI79 Q5SZS6 Q96PH9 Q495T7 Q495T8
Accessions	CAC09978 EAW56080 EAW56081 EAW56082 Q495T6 AF336981 AAL08942 AK093058 BAG52644 BC101027 AAI01028 BC101028 AAI01029 BC101029 AAI01030 BC101030 AAI01031 DB089501 XM_011542115 XP_011540417 XM_011542116 XP_011540418 XM_011542117 XP_011540419 XM_011542118 XP_011540420 XM_011542119 XP_011540421 XM_011542120 XP_011540422 XM_011542121 XP_011540423 XM_011542122 XP_011540424 XM_011542123 XP_011540425 XM_011542124 XP_011540426 XM_011542125 XP_011540427 XM_011546399 XP_011544701 XM_011546400 XP_011544702 XM_011546401 XP_011544703 XM_011546402 XP_011544704 XM_011546403 XP_011544705 XM_011546404 XP_011544706 XM_011546405 XP_011544707 XM_011546406 XP_011544708 XM_011546407 XP_011544709 XM_011546408 XP_011544710 XM_011546409 XP_011544711 XM_011546410 XP_011544712 XR_946752 XR_946753 XR_946754 XR_951571 XR_951572 XR_951573 NM_033467 NP_258428
Function	Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity). {ECO:0000250}.
Subcellular Location	Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteollytic cleavage also exists. {ECO:0000250}.
Tissue Specificity	Predominantly expressed in testis. Weakly expressed in brain, kidney and heart. {ECO:0000269|PubMed:11560781}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Membrane metallo-endopeptidase-like 1, MMEL1, Human, ELISA Kit - E2033h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 31.2-2000 pg/ml

Custom Human Neprilysin-2 ELISA - ELH-Neprilysin2 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

membrane metallo-endopeptidase-like 1, ELISA Kit - MBS9330015 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Selenoprotein P1, Plasma (SEPP1) - SEB809Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.31ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human MMEL1 ELISA Kit (Sandwich ELISA) - LS-F19092 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 31.2 Range 31.2-2000 pg/ml

Mouse MMEL1 ELISA Kit (Custom ELISA) - LS-F19091 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 31.2-2000 pg/ml

Rat MMEL1 ELISA Kit (Custom ELISA) - LS-F19090 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 31.2-2000 pg/ml

Human Membrane metallo-endopeptidase-like 1 ELISA Kit - abx251391 from Abbexa Category ELISA Kit Range 31.2 pg/ml - 2000 pg/ml

Custom Human Neprilysin-2 Elisa kit - orb305346 from Biorbyt Category ELISA Kit Prices $1,148.00, $1,981.00, $4,284.00 Sizes 96 assays, 192 assays, 480 assays

Human Neprilysin-2 ELISA - RAB1591 from Sigma-Aldrich Prices $615.00 Sizes 1 kt

Human Membrane metallo-endopeptidase-like 1 ELISA Kit - EKE52214 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 10 pg/mL Range 31.2-2000 pg/ml

MMEL1 - EKH4122 from Nordic BioSite Sensitivity 18.75pg/ml Range 31.2-2000pg/ml

Custom Human Neprilysin-2 ELISA - ELH-Neprilysin2-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human MMEL1 ELISA Kit - E024118 from Biobool Category ELISA Kit Sensitivity <18.75pg/ml

Human NEP2 ELISA Kit - E025969 from Biobool Category ELISA Kit

MMEL1 ELISA Kit (Human) (OKEH04755) - OKEH04755 from Aviva Systems Biology Category ELISA Kit Prices $425.00 Sizes 96 wells Sensitivity < 15.6 pg/mL Range 31.2 - 2,000 pg/mL

Membrane metallo-endopeptidase-like 1, ELISA Kit - MBS2885386 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 31.2-2000 pg/ml

Membrane metallo-endopeptidase-like 1, ELISA Kit - MBS764964 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 18.75pg/ml Range 31.2-2000pg/ml

Human MMEL1 ELISA Kit (Sandwich ELISA) - LS-F35253 from LifeSpan Bioscience Category ELISA Kit Sensitivity 18.75 Range 31.2-2000 pg/ml

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