MMEL1

Gene Symbol MMEL1
Entrez Gene 79258
Alt Symbol MMEL2, NEP2, NEPII, NL1, NL2, SEP
Species Human
Gene Type protein-coding
Description membrane metallo-endopeptidase-like 1
Other Description NEP2(m)|membrane metallo-endopeptidase-like 2|neprilysin II|neprilysin-2|soluble secreted endopeptidase|zinc metallopeptidase
Swissprots Q495T6 B9DI79 Q5SZS6 Q96PH9 Q495T7 Q495T8
Accessions CAC09978 EAW56080 EAW56081 EAW56082 Q495T6 AF336981 AAL08942 AK093058 BAG52644 BC101027 AAI01028 BC101028 AAI01029 BC101029 AAI01030 BC101030 AAI01031 DB089501 XM_011542115 XP_011540417 XM_011542116 XP_011540418 XM_011542117 XP_011540419 XM_011542118 XP_011540420 XM_011542119 XP_011540421 XM_011542120 XP_011540422 XM_011542121 XP_011540423 XM_011542122 XP_011540424 XM_011542123 XP_011540425 XM_011542124 XP_011540426 XM_011542125 XP_011540427 XM_011546399 XP_011544701 XM_011546400 XP_011544702 XM_011546401 XP_011544703 XM_011546402 XP_011544704 XM_011546403 XP_011544705 XM_011546404 XP_011544706 XM_011546405 XP_011544707 XM_011546406 XP_011544708 XM_011546407 XP_011544709 XM_011546408 XP_011544710 XM_011546409 XP_011544711 XM_011546410 XP_011544712 XR_946752 XR_946753 XR_946754 XR_951571 XR_951572 XR_951573 NM_033467 NP_258428
Function Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Single-pass type II membrane protein. Secreted. Note=A secreted form produced by proteollytic cleavage also exists. {ECO:0000250}.
Tissue Specificity Predominantly expressed in testis. Weakly expressed in brain, kidney and heart. {ECO:0000269|PubMed:11560781}.

Human Neprilysin-like Protease beta full length protein - ab164012 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164012 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Neprilysin-2/MMEL1 Recombinant Protein - H00079258-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human Neprilysin-2/MMEL1, CF - 2340-ZN-010 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Gly69-Trp770, with an N-terminal 6-His tag

MMEL1 Blocking Peptide - 33R-2809 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Recombinant Human ANGPTL4 - BP000053-CYT-249 from Syd Labs

Category Protein
Prices $160.00, $4,800.00
Sizes 10 µg, 1 mg
Source E. coli-derived.
Species Human

Recombinant Human ANGPTL4锛孒EK - BP000053-CYT-698 from Syd Labs

Category Protein
Prices $160.00, $4,800.00
Sizes 10 µg, 1 mg
Source HEK293-derived.
Species Human

Recombinant Human Membrane Metallo-Endopeptidase-Like 1, His-tagged - MMEL1-1981H from Creative Biomart

Category Protein
Source Murine myeloma cellline, NS0-derived.

Recombinant Human MMEL1, His-tagged - MMEL1-384H from Creative Biomart

Category Protein
Source NSO cells
Species Human

Recombinant Selenoprotein P1, Plasma (SEPP1) - RPB809Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human Membrane metallo-endopeptidase-like 1(MMEL1) - CSB-YP014654HU CSB-EP014654HU CSB-BP014654HU CSB-MP014654HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Neprilysin-2/MMEL1 Protein, CF - 2340-ZN from R&D Systems

Category Protein
Prices $329.00
Sizes 10 µg
Source Mouse myeloma cell line, NS0-derived Gly69-Trp770, with an N-terminal 6-His tag
Species Human

Neprilysin-2/MMEL1 Recombinant Protein Antigen - NBP1-92126PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Neprilysin-2/MMEL1 Recombinant Protein Antigen - NBP1-92125PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

MMEL1-Blocking-Peptide-N-term - BP20146a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

MMEL1 Peptide, Human - M34GP09587H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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