Gene Symbol | TRPV2 |
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Entrez Gene | 51393 |
Alt Symbol | VRL, VRL-1, VRL1 |
Species | Human |
Gene Type | protein-coding |
Description | transient receptor potential cation channel, subfamily V, member 2 |
Other Description | OTRPC2|osm-9-like TRP channel 2|transient receptor potential cation channel subfamily V member 2|vanilloid receptor-like protein 1 |
Swissprots | A8K0Z0 Q9Y5S1 A6NML2 Q9Y670 |
Accessions | CAB70426 EAX04507 EAX04508 EAX04509 Q9Y5S1 AF103906 AAD41724 AF129112 AAD26363 AJ487963 CAD32310 AK001896 BAG50989 AK289705 BAF82394 BC018926 AAH18926 BC051305 AAH51305 DQ893607 ABM84533 DQ895145 ABM86071 XM_005256676 XP_005256733 XM_005256677 XP_005256734 XM_005256678 XP_005256735 XM_006721541 XP_006721604 XM_006721542 XP_006721605 XM_006721543 XP_006721606 XM_011523922 XP_011522224 XM_011523923 XP_011522225 XM_011523924 XP_011522226 XM_011523925 XP_011522227 NM_016113 NP_057197 |
Function | Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. {ECO:0000269|PubMed:10201375}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}. |
Top Pathways | Inflammatory mediator regulation of TRP channels |
Mouse VRL1 / TRPV2 ELISA Kit (Sandwich ELISA) - LS-F7807 from LifeSpan Bioscience
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Transient receptor potential cation channel subfamily V member 2 (TRPV2), Human, ELISA Kit - CSB-EL025094HU from ARP American Research Products
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transient receptor potential cation channel, subfamily V, member 2, ELISA Kit - MBS938616 from MyBioSource
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ELISA Kit for Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) - SEF840Mu from Uscn Life Science Inc.
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Human Transient receptor potential cation channel subfamily V member 2(TRPV2) ELISA kit - CSB-EL025094HU from Cusabio
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Human Transient receptor potential cation channel subfamily V member 2 (TRPV2) ELISA Kit - EKC35857 from Biomatik
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Human TRPV2 ELISA Kit - E039025 from Biobool
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anti-Trpv2 antibody - ARG64679 from Arigo Biolaboratories
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TRPV2 ELISA Kit (Human) (OKCA01557) - OKCA01557 from Aviva Systems Biology
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