TRPV2

Gene Symbol	TRPV2
Entrez Gene	51393
Alt Symbol	VRL, VRL-1, VRL1
Species	Human
Gene Type	protein-coding
Description	transient receptor potential cation channel, subfamily V, member 2
Other Description	OTRPC2|osm-9-like TRP channel 2|transient receptor potential cation channel subfamily V member 2|vanilloid receptor-like protein 1
Swissprots	A8K0Z0 Q9Y5S1 A6NML2 Q9Y670
Accessions	CAB70426 EAX04507 EAX04508 EAX04509 Q9Y5S1 AF103906 AAD41724 AF129112 AAD26363 AJ487963 CAD32310 AK001896 BAG50989 AK289705 BAF82394 BC018926 AAH18926 BC051305 AAH51305 DQ893607 ABM84533 DQ895145 ABM86071 XM_005256676 XP_005256733 XM_005256677 XP_005256734 XM_005256678 XP_005256735 XM_006721541 XP_006721604 XM_006721542 XP_006721605 XM_006721543 XP_006721606 XM_011523922 XP_011522224 XM_011523923 XP_011522225 XM_011523924 XP_011522226 XM_011523925 XP_011522227 NM_016113 NP_057197
Function	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. {ECO:0000269|PubMed:10201375}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}.
Top Pathways	Inflammatory mediator regulation of TRP channels

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

VRL1 / TRPV2 Antibody Blocking Peptide - LS-E2924 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

VRL1 / TRPV2 Antibody Blocking Peptide - LS-E29443 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

VRL1 / TRPV2 Antibody Blocking Peptide - LS-E29466 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

VRL1 / TRPV2 Antibody Blocking Peptide - LS-E29465 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

VRL1 / TRPV2 Antibody Blocking Peptide - LS-E26819 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRPV2-Antibody-N-term-Blocking-peptide - BP14049a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VRL1 blocking peptide - GTX88463-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

VRL1 Peptide - AC21-1650-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TRPV2 / VRL1 Control Peptide - AP07065CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

TRPV2 Peptide - 42-750P from ProSci Category Peptide

TRPV2 fusion protein - Ag8855 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TRPV2 fusion protein - ag8864 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human TRPV2, His-tagged - TRPV2-3439H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TRPV2 - TRPV2-808H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) - RPF840Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Transient Receptor Potential Cation Channel Subfamily V, Member 2 (TRPV2) - RPF840Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

TRPV2, Peptide - MBS425331 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Vanilloid Receptor Like Protein 1, Peptide - MBS658206 from MyBioSource Category Protein Prices $340.00 Sizes 100 µg Species Human

Vanilloid Receptor Like Protein 1, Peptide - MBS659822 from MyBioSource Category Protein Prices $275.00, $335.00 Sizes 50 µg, 100 µg Source Rat Species Human, Rat

VRL1 Protein - NBP1-92576PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

TRPV2 Peptide, Human - M34GP16690H from Creative Peptides Category Peptide Source Synthetic. Species Human

Trpv2 Immunizing peptide - orb55001 from Biorbyt Category Peptide

TRPV2 Immunizing peptide - orb55106 from Biorbyt Category Peptide

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