TRPV2

Gene Symbol TRPV2
Entrez Gene 51393
Alt Symbol VRL, VRL-1, VRL1
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily V, member 2
Other Description OTRPC2|osm-9-like TRP channel 2|transient receptor potential cation channel subfamily V member 2|vanilloid receptor-like protein 1
Swissprots A8K0Z0 Q9Y5S1 A6NML2 Q9Y670
Accessions CAB70426 EAX04507 EAX04508 EAX04509 Q9Y5S1 AF103906 AAD41724 AF129112 AAD26363 AJ487963 CAD32310 AK001896 BAG50989 AK289705 BAF82394 BC018926 AAH18926 BC051305 AAH51305 DQ893607 ABM84533 DQ895145 ABM86071 XM_005256676 XP_005256733 XM_005256677 XP_005256734 XM_005256678 XP_005256735 XM_006721541 XP_006721604 XM_006721542 XP_006721605 XM_006721543 XP_006721606 XM_011523922 XP_011522224 XM_011523923 XP_011522225 XM_011523924 XP_011522226 XM_011523925 XP_011522227 NM_016113 NP_057197
Function Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. {ECO:0000269|PubMed:10201375}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}.
Top Pathways Inflammatory mediator regulation of TRP channels

VRL-1 (G-4) - sc-390439 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VRL-1 (G-4): sc-390439. Western blot analysis of VRL-1 expression in Jurkat (A) and Ramos (B) whole cell lysates.

VRL-1 (G-20) - sc-22521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VRL-1 (G-20): sc-22521. Western blot analysis of VRL-1 expression in mouse cerebellum tissue extract.

VRL-1 (D-20) - sc-22520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VRL-1 (D-20): sc-22520. Western blot analysis of VRL-1 expression in mouse cerebellum tissue extract.

VRL-1 (H-105) - sc-30155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VRL-1 (H-105): sc-30155. Western blot analysis of VRL-1 expression in mouse cerebellum tissue extract.

Anti-VRL1 antibody - ab63149 from Abcam

Host Rabbit
Clonality Polyclonal
ab63149 staining VRL1 (green) in Human monocyte-derived dendritic cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with acetone. Samples were incubated with primary antibody (1/200). A FITC-conjugated anti-rabbit IgG was used as the secondary antibody (1/200). Nuclei were counterstained by DAPI (blue).

Anti-VRL1 antibody - ab63125 from Abcam

Host Sheep
Clonality Polyclonal

Anti-VRL1 antibody - ab74843 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-VRL1 antibody - ab150738 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate tissue labelled with ab150738 at 5 µg/ml.

Anti-VRL1 antibody - ab62046 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab62046 at 10µg/ml staining VRL1 in human Dorsal root ganglion by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

Anti-VRL1 / TRPV2 Antibody (Internal) IHC-plus™ - LS-A8739 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TRPV2 antibody LS-A8739 IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-VRL1 / TRPV2 Antibody (aa42-624) - LS-C313107 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
VRL1 / TRPV2 antibody. IHC(P): Human Intestinal Cancer Tissue.

Anti-VRL1 / TRPV2 Antibody IHC-plus™ - LS-B4211 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TRPV2 antibody IHC of human small intestine, submucosal plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4211 concentration 10 ug/ml.

Anti-VRL1 / TRPV2 Antibody (C-Terminus) - LS-C18443 from LifeSpan Bioscience

Prices $590.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, APC) - LS-C207816 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, Biotin) - LS-C207815 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, AP) - LS-C207814 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (N-Terminus) - LS-C122530 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, PE) - LS-C207820 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, FITC) - LS-C207817 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81, Azide-free, HRP) - LS-C207818 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa51-81) - LS-C330262 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VRL1 / TRPV2 Antibody (aa743-756) - LS-C112764 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TRPV2 antibody (2 ug/ml) staining of Rat Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-VRL1 / TRPV2 Antibody (Internal) IHC-plus™ - LS-A8738 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TRPV2 antibody LS-A8738 IHC of human dorsal root ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-VRL1 / TRPV2 Antibody (aa52-81) - LS-C160238 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TRPV2 Antibody western blot of MDA-MB435 cell line lysates (35 ug/lane). The TRPV2 antibody detected the TRPV2 protein (arrow).

Anti-VRL1 / TRPV2 Antibody (N-Terminus) IHC-plus™ - LS-A8597 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-VRL1 / TRPV2 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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