TRPV2

Gene Symbol TRPV2
Entrez Gene 51393
Alt Symbol VRL, VRL-1, VRL1
Species Human
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily V, member 2
Other Description OTRPC2|osm-9-like TRP channel 2|transient receptor potential cation channel subfamily V member 2|vanilloid receptor-like protein 1
Swissprots A8K0Z0 Q9Y5S1 A6NML2 Q9Y670
Accessions CAB70426 EAX04507 EAX04508 EAX04509 Q9Y5S1 AF103906 AAD41724 AF129112 AAD26363 AJ487963 CAD32310 AK001896 BAG50989 AK289705 BAF82394 BC018926 AAH18926 BC051305 AAH51305 DQ893607 ABM84533 DQ895145 ABM86071 XM_005256676 XP_005256733 XM_005256677 XP_005256734 XM_005256678 XP_005256735 XM_006721541 XP_006721604 XM_006721542 XP_006721605 XM_006721543 XP_006721606 XM_011523922 XP_011522224 XM_011523923 XP_011522225 XM_011523924 XP_011522226 XM_011523925 XP_011522227 NM_016113 NP_057197
Function Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. {ECO:0000269|PubMed:10201375}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250}.
Top Pathways Inflammatory mediator regulation of TRP channels

VRL-1 CRISPR/Cas9 KO Plasmid (h) - sc-401648 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 HDR Plasmid (h) - sc-401648-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 Double Nickase Plasmid (h) - sc-401648-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 Double Nickase Plasmid (h2) - sc-401648-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 CRISPR Activation Plasmid (h) - sc-401648-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 CRISPR Activation Plasmid (h2) - sc-401648-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 Lentiviral Activation Particles (h) - sc-401648-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 Lentiviral Activation Particles (h2) - sc-401648-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

VRL-1 siRNA (h) - sc-42678 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VRL-1 shRNA Plasmid (h) - sc-42678-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

VRL-1 shRNA (h) Lentiviral Particles - sc-42678-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU014011 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22064 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22064 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TRPV2 siRNA (Human) - CRH9744 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

VRL1 RNAi - H00051393-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TRPV2 - MBS8212827 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRPV2 (NM_016113.4) - SHH435756 from Creative biogene

Category siRNA
Species Reactivities Human

Human TRPV2 siRNA - orb270246 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRPV2 shRNA Plasmid (Human) - CHH9744 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRPV2 miRNA 3'UTR clone - MiUTR3H-08650 from Creative biogene

Species Reactivities Human
Search more