UBA7

Gene Symbol	UBA7
Entrez Gene	7318
Alt Symbol	D8, UBA1B, UBE1L, UBE2
Species	Human
Gene Type	protein-coding
Description	ubiquitin-like modifier activating enzyme 7
Other Description	UBA1, ubiquitin-activating enzyme E1 homolog B|UBA7, ubiquitin-activating enzyme E1|ubiquitin-activating enzyme 7|ubiquitin-activating enzyme E1 homolog|ubiquitin-activating enzyme E1-related protein|ubiquitin-activating enzyme-2|ubiquitin-like modifier-activating enzyme 7
Swissprots	P41226 Q9BRB2
Accessions	AAG49557 EAW65023 EAW65024 P41226 BC006378 AAH06378 BM152341 BT007026 AAP35672 CA425139 DQ893307 ABM84233 DQ893707 ABM84633 L13852 AAA75388 XM_005265430 XP_005265487 XM_006713321 XP_006713384 XM_011534070 XP_011532372 XM_011534071 XP_011532373 XM_011534072 XP_011532374 XM_011534073 XP_011532375 NM_003335 NP_003326
Function	Activates ubiquitin by first adenylating with ATP its C- terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein. {ECO:0000269|PubMed:16254333, ECO:0000269|PubMed:20133869}.
Tissue Specificity	Expressed in a variety of normal and tumor cell types, but is reduced in lung cancer cell lines.
Top Pathways	Ubiquitin mediated proteolysis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Ube1L full length protein - ab188684 from Abcam Category Protein Prices $572.00 Sizes 25 µg Source Baculovirus infected Sf21 cells Species Human

Human Ube1L full length protein - ab152780 from Abcam Category Protein Source Wheat germ Species Human

Human Ube1L protein fragment - ab152781 from Abcam Category Protein Source Wheat germ Species Human

UBE1L / UBA7 Antibody Blocking Peptide - LS-E3058 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ISG15 Activating Enzyme/UBE1L Protein - H00007318-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ISG15 Activating Enzyme/UBE1L Protein - H00007318-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

UBA7-Antibody-N-term-Blocking-Peptide - BP14193a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human ISG15 E1/UBE1L, CF - E-309-025 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived,

Recombinant Human GST-ISG15 E1/UBE1L, CF - E-308-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 9 (baculovirus)-derived, Contains an N-terminal GST (glutathione S-transferase) tag

UBA7 peptide - orb218065 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human

UBA7 Blocking Peptide - abx063396 from Abbexa Category Peptide Species Human

UBA7 / UBE1L - H00007318-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

UBA7 / UBE1L - H00007318-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

UBA7 / UBE1L - H00007318-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

UBA7 / UBE1L - H00007318-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

UBA7 / UBE1L - H00007318-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

UBA7 fusion protein - ag8332 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

UBA7 fusion protein - Ag8692 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human UBA7, GST-tagged - UBA7-833H from Creative Biomart Category Protein Source Sf9 insect cells using baculovirus Species Human

Recombinant Human UBA7, His-tagged - UBA7-171H from Creative Biomart Category Protein Source Insect cells Species Human

Recombinant Human UBA7, His-tagged - UBA7-629H from Creative Biomart Category Protein Source E. coli.

Recombinant Ubiquitin Activating Enzyme E1 Like Protein (UBE1L) - RPB027Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Ubiquitin Activating Enzyme E1 Like Protein (UBE1L) - RPB027Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Ubiquitin Activating Enzyme E1 Like Protein (UBE1L) - RPB027Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

UBA7 Blocking Peptide - CBP2202 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

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