SMPD2

Gene Symbol	SMPD2
Entrez Gene	6610
Alt Symbol	ISC1, NSMASE, NSMASE1
Species	Human
Gene Type	protein-coding
Description	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Other Description	N-SMase|lyso-PAF-PLC|lyso-platelet-activating factor-phospholipase C|neutral sphingomyelinase|sphingomyelin phosphodiesterase 2
Swissprots	O60906 Q9BWR3 Q5TED1
Accessions	EAW48346 O60906 AJ222801 CAA10995 AK310148 AK313515 BAG36295 BC000038 AAH00038 CA314251 DA672570 DQ891879 ABM82805 HQ447883 ADQ32367 XM_005267109 XP_005267166 XM_011536079 XP_011534381 XR_942566 NM_003080 NP_003071
Function	Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Subcellular Location	Membrane; Multi-pass membrane protein.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMPD2 ELISA Kit (Sandwich ELISA) - LS-F6866 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.067 ng/ml Range 0.156-10 ng/ml

Rat SMPD2 ELISA Kit (Sandwich ELISA) - LS-F6965 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.068 ng/ml Range 0.156-10 ng/ml

Human NSMASE ELISA Kit - abx152557 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Neutral Sphingomyelinase (NSMASE), Human, ELISA Kit - SED058Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.067ng/mL Range 0.156-10ng/mL

Neutral Sphingomyelinase, ELISA Kit - MBS056619 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS074574 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS099729 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS106908 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS105123 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS102596 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase, ELISA Kit - MBS103643 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Neutral Sphingomyelinase (NSMASE), ELISA Kit - MBS2022949 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.067ng/mL. Range 0.156-10ng/mL

sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) , ELISA Kit - MBS9316864 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml Range 0.25ng/ml-8ng/ml

ELISA Kit for Neutral Sphingomyelinase (NSMASE) - SED058Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.067ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Neutral Sphingomyelinase (NSMASE) - SED058Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.068ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Neutral Sphingomyelinase (NSMASE) - SED058Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.067ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Neutral Sphingomyelinase (NSMASE) ELISA Kit - EKU06277 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.067 ng/mL Range 0.156-10 ng/mL

Neutral Sphingomyelinase (NSMASE), Human, ELISA Kit - DL-NSMASE-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human NSMASE ELISA Kit - abx570827 from Abbexa Category ELISA Kit Sensitivity 0.067 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human NSMASE ELISA Kit - E026404 from Biobool Category ELISA Kit Sensitivity Typically less than 0.067ng/mL.

Human SMPD2 ELISA Kit - E036427 from Biobool Category ELISA Kit

SMPD2 ELISA Kit (Human) (OKCD00366) - OKCD00366 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.067 ng/mL Range 0.156-10 ng/mL

NSMASE ELISA Kit (Human) (OKDD00439) - OKDD00439 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.067 ng/mL Range 0.156-10 ng/mL

Human Sphingomyelin phosphodiesterase 2 (SMPD2) ELISA Kit - AE18065HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.067 ng/mL Range 0.156-10 ng/mL

Neutral Sphingomyelinase (NSMASE), ELISA Kit - MBS451206 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.067ng/mL Range 0.156-10ng/mL

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