SMPD2

Gene Symbol SMPD2
Entrez Gene 6610
Alt Symbol ISC1, NSMASE, NSMASE1
Species Human
Gene Type protein-coding
Description sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Other Description N-SMase|lyso-PAF-PLC|lyso-platelet-activating factor-phospholipase C|neutral sphingomyelinase|sphingomyelin phosphodiesterase 2
Swissprots O60906 Q9BWR3 Q5TED1
Accessions EAW48346 O60906 AJ222801 CAA10995 AK310148 AK313515 BAG36295 BC000038 AAH00038 CA314251 DA672570 DQ891879 ABM82805 HQ447883 ADQ32367 XM_005267109 XP_005267166 XM_011536079 XP_011534381 XR_942566 NM_003080 NP_003071
Function Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Subcellular Location Membrane; Multi-pass membrane protein.
Top Pathways Sphingolipid signaling pathway, Sphingolipid metabolism

N-SMase CRISPR/Cas9 KO Plasmid (h) - sc-405568 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase HDR Plasmid (h) - sc-405568-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase Double Nickase Plasmid (h) - sc-405568-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase Double Nickase Plasmid (h2) - sc-405568-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase CRISPR Activation Plasmid (h) - sc-405568-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase CRISPR Activation Plasmid (h2) - sc-405568-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase Lentiviral Activation Particles (h) - sc-405568-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase Lentiviral Activation Particles (h2) - sc-405568-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

N-SMase siRNA (h) - sc-106277 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-SMase shRNA Plasmid (h) - sc-106277-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

N-SMase shRNA (h) Lentiviral Particles - sc-106277-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

nSMase RNAi - H00006610-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU120741 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19800 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19800 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SMPD2 siRNA (Human) - CRH4493 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SMPD2 - MBS8210242 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SMPD2 (NM_003080.2) - SHH413568 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SMPD2(NM_003080.2) - SHL019538 from Creative biogene

Category siRNA
Species Reactivities Human

SMPD2 shRNA Plasmid (Human) - CHH4493 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SMPD2 miRNA 3'UTR clone - MiUTR1H-09662 from Creative biogene

Species Reactivities Human

SMPD2 miRNA 3'UTR clone - MiUTR2H-09662 from Creative biogene

Species Reactivities Human
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