SMPD2

Gene Symbol	SMPD2
Entrez Gene	6610
Alt Symbol	ISC1, NSMASE, NSMASE1
Species	Human
Gene Type	protein-coding
Description	sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
Other Description	N-SMase|lyso-PAF-PLC|lyso-platelet-activating factor-phospholipase C|neutral sphingomyelinase|sphingomyelin phosphodiesterase 2
Swissprots	O60906 Q9BWR3 Q5TED1
Accessions	EAW48346 O60906 AJ222801 CAA10995 AK310148 AK313515 BAG36295 BC000038 AAH00038 CA314251 DA672570 DQ891879 ABM82805 HQ447883 ADQ32367 XM_005267109 XP_005267166 XM_011536079 XP_011534381 XR_942566 NM_003080 NP_003071
Function	Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2- lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso- sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
Subcellular Location	Membrane; Multi-pass membrane protein.
Top Pathways	Sphingolipid signaling pathway, Sphingolipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human nSMase full length protein - ab114871 from Abcam Category Protein Source Wheat germ Species Human

SMPD2 Antibody Blocking Peptide - LS-E7126 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMPD2 Antibody Blocking Peptide - LS-E16598 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SMPD2 Antibody Blocking Peptide - LS-E16599 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human nSMase Protein - H00006610-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SMPD2-Antibody-N-term-Blocking-Peptide - BP2822a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SMPD2 Blocking Peptide - 33R-8123 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SMPD2 Blocking Peptide - 33R-6158 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human NSMASE Protein - abx068273 from Abbexa Category Protein Source E.coli Species Human

SMPD2 - H00006610-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SMPD2 - H00006610-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Neutral Sphingomyelinase (NSMASE), Human - 20-8643 from ARP American Research Products Category Protein Prices $519.00 Sizes 50 µg Source E.coli Species Human

SMPD2 fusion protein - ag7367 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

SMPD2 fusion protein - Ag7482 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SMPD2 - SMPD2-29731TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Neutral Sphingomyelinase (NSMASE) - RPD058Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Neutral Sphingomyelinase (NSMASE) - RPD058Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Neutral Sphingomyelinase (NSMASE) - RPD058Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Neutral Sphingomyelinase (NSMASE) - RPU143035 from Biomatik Category Protein Prices $247.50, $495.00, $742.50 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

nSMase Recombinant Protein Antigen - NBP1-87810PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SMPD2-Antibody-Center-Blocking-Peptide - BP2822c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SMPD2 Peptide, Human - M34GP14769H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Neutral Sphingomyelinase (NSMASE) - RPU43035 from Biomatik Category Protein Prices $198.00, $387.00, $619.00, $738.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

SMPD2 Recombinant Protein (OPCD05816) - OPCD05816 from Aviva Systems Biology Category Protein Source E.coli Species Human

Neutral Sphingomyelinase (NSMASE), Recombinant Protein - MBS2010016 from MyBioSource Category Protein Prices $190.00, $405.00, $625.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Search more