Gene Symbol | SIVA1 |
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Entrez Gene | 10572 |
Alt Symbol | CD27BP, SIVA, Siva-1, Siva-2 |
Species | Human |
Gene Type | protein-coding |
Description | SIVA1, apoptosis-inducing factor |
Other Description | CD27-binding (Siva) protein|apoptosis regulatory protein Siva |
Swissprots | Q96P98 O15304 Q9UPD6 |
Accessions | DAA01049 EAW81877 EAW81878 EAW81879 EAW81880 O15304 AF033111 AAD50057 AF401214 AAL02171 AK124078 AK128704 AK223332 BAD97052 AK300415 BAG62144 AK316457 BAH14828 AK316550 BAG65628 BC034562 AAH34562 BU195069 CK001877 HQ447960 ADQ32443 XM_011536360 XP_011534662 NM_006427 NP_006418 NM_021709 NP_068355 |
Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis. {ECO:0000269|PubMed:12011449, ECO:0000269|PubMed:14739602, ECO:0000269|PubMed:15034012, ECO:0000269|PubMed:15958577, ECO:0000269|PubMed:16491128}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15034012}. Nucleus {ECO:0000269|PubMed:15034012}. Note=In the nucleus, accumulates in dot-like structures. |
Tissue Specificity | Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. |
Siva-1 Antibody - 12532 from Cell Signaling Technology
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Siva (F-1) - sc-376260 from Santa Cruz Biotechnology
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Siva (H-9) - sc-514375 from Santa Cruz Biotechnology
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Siva (FL-175) - sc-48767 from Santa Cruz Biotechnology
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Siva (M-175) - sc-48768 from Santa Cruz Biotechnology
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Siva (N-19) - sc-7250 from Santa Cruz Biotechnology
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Siva (C-20) - sc-7436 from Santa Cruz Biotechnology
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Anti-SIVA antibody - ab67620 from Abcam
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Anti-SIVA antibody [1B10] - ab170419 from Abcam
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Anti-SIVA1 / SIVA Antibody (clone 1C9) - LS-C174829 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (aa1-175) - LS-C315030 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 2E4) - LS-C174830 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 1D6) - LS-C174832 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 2D3) - LS-C174834 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 2F8) - LS-C338207 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 1G8) - LS-C174831 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 2B7) - LS-C338209 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (clone 1B10) - LS-C338208 from LifeSpan Bioscience
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Anti-SIVA1 / SIVA Antibody (N-Terminus) - LS-C144462 from LifeSpan Bioscience
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SIVA Antibody - H00010572-B01P from Novus Biologicals
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SIVA Antibody - H00010572-B02P from Novus Biologicals
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SIVA Antibody - H00010572-A01 from Novus Biologicals
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SIVA Antibody - NBP2-41150 from Novus Biologicals
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Anti-SIVA antibody produced in mouse - SAB1400393 from Sigma-Aldrich
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Anti-SIVA1 antibody produced in chicken - SAB3500697 from Sigma-Aldrich
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