Gene Symbol | SIVA1 |
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Entrez Gene | 10572 |
Alt Symbol | CD27BP, SIVA, Siva-1, Siva-2 |
Species | Human |
Gene Type | protein-coding |
Description | SIVA1, apoptosis-inducing factor |
Other Description | CD27-binding (Siva) protein|apoptosis regulatory protein Siva |
Swissprots | Q96P98 O15304 Q9UPD6 |
Accessions | DAA01049 EAW81877 EAW81878 EAW81879 EAW81880 O15304 AF033111 AAD50057 AF401214 AAL02171 AK124078 AK128704 AK223332 BAD97052 AK300415 BAG62144 AK316457 BAH14828 AK316550 BAG65628 BC034562 AAH34562 BU195069 CK001877 HQ447960 ADQ32443 XM_011536360 XP_011534662 NM_006427 NP_006418 NM_021709 NP_068355 |
Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis. {ECO:0000269|PubMed:12011449, ECO:0000269|PubMed:14739602, ECO:0000269|PubMed:15034012, ECO:0000269|PubMed:15958577, ECO:0000269|PubMed:16491128}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15034012}. Nucleus {ECO:0000269|PubMed:15034012}. Note=In the nucleus, accumulates in dot-like structures. |
Tissue Specificity | Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. |
SIVA 293T Cell Transient Overexpression Lysate(Denatured) - H00010572-T01 from Acris Antibodies
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SIVA 293T Cell Transient Overexpression Lysate(Denatured) - H00010572-T02 from Acris Antibodies
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SIVA1 overexpression lysate - LY411940 from Acris Antibodies
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SIVA1 overexpression lysate - LY416652 from Acris Antibodies
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SIVA1 293 Cell Lysate - 405942 from ABBIOTEC
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SIVA Overexpression Lysate (Denatured) - H00010572-T02 from Novus Biologicals
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SIVA Overexpression Lysate (Denatured) - H00010572-T01 from Novus Biologicals
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SIVA Overexpression Lysate (Native) - NBL1-15981 from Novus Biologicals
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SIVA1 Over-expression Lysate Product - GWB-81D1C8 from Genway Biotech
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SIVA Overexpression Lysate (Native) - NBP2-10413 from Novus Biologicals
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SIVA Overexpression Lysate (Denatured) - H00010572-T03 from Novus Biologicals
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Panoply™ Human SIVA1 Knockdown Stable Cell Line - CSC-DC014275 from Creative biogene
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SIVA1 KO Cell Lysate-HEK293T - CLKO-0851 from Creative biogene
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