SIVA1

Gene Symbol	SIVA1
Entrez Gene	10572
Alt Symbol	CD27BP, SIVA, Siva-1, Siva-2
Species	Human
Gene Type	protein-coding
Description	SIVA1, apoptosis-inducing factor
Other Description	CD27-binding (Siva) protein|apoptosis regulatory protein Siva
Swissprots	Q96P98 O15304 Q9UPD6
Accessions	DAA01049 EAW81877 EAW81878 EAW81879 EAW81880 O15304 AF033111 AAD50057 AF401214 AAL02171 AK124078 AK128704 AK223332 BAD97052 AK300415 BAG62144 AK316457 BAH14828 AK316550 BAG65628 BC034562 AAH34562 BU195069 CK001877 HQ447960 ADQ32443 XM_011536360 XP_011534662 NM_006427 NP_006418 NM_021709 NP_068355
Function	Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis. {ECO:0000269|PubMed:12011449, ECO:0000269|PubMed:14739602, ECO:0000269|PubMed:15034012, ECO:0000269|PubMed:15958577, ECO:0000269|PubMed:16491128}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15034012}. Nucleus {ECO:0000269|PubMed:15034012}. Note=In the nucleus, accumulates in dot-like structures.
Tissue Specificity	Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Siva CRISPR/Cas9 KO Plasmid (h) - sc-403496 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva HDR Plasmid (h) - sc-403496-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva Double Nickase Plasmid (h) - sc-403496-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva Double Nickase Plasmid (h2) - sc-403496-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva CRISPR Activation Plasmid (h) - sc-403496-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva CRISPR Activation Plasmid (h2) - sc-403496-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva Lentiviral Activation Particles (h) - sc-403496-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva Lentiviral Activation Particles (h2) - sc-403496-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Siva siRNA (h) - sc-37385 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Siva shRNA Plasmid (h) - sc-37385-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Siva shRNA (h) Lentiviral Particles - sc-37385-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

SIVA RNAi - H00010572-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

SIVA RNAi - H00010572-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU082411 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19366 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19366 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00548 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr00548

SIVA1 siRNA (Human) - CRH7192 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SIVA1 - MBS8205465 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SIVA1(NM_021709.2) - SHR226656 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SIVA1(NM_006427.3) - SHR226930 from Creative biogene Category siRNA Species Reactivities Human

SIVA1 shRNA Plasmid (Human) - CHH7192 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

SIVA1 miRNA 3'UTR clone - MiUTR1H-09416 from Creative biogene Species Reactivities Human

SIVA1 miRNA 3'UTR clone - MiUTR1H-09417 from Creative biogene Species Reactivities Human

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