Gene Symbol | SIVA1 |
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Entrez Gene | 10572 |
Alt Symbol | CD27BP, SIVA, Siva-1, Siva-2 |
Species | Human |
Gene Type | protein-coding |
Description | SIVA1, apoptosis-inducing factor |
Other Description | CD27-binding (Siva) protein|apoptosis regulatory protein Siva |
Swissprots | Q96P98 O15304 Q9UPD6 |
Accessions | DAA01049 EAW81877 EAW81878 EAW81879 EAW81880 O15304 AF033111 AAD50057 AF401214 AAL02171 AK124078 AK128704 AK223332 BAD97052 AK300415 BAG62144 AK316457 BAH14828 AK316550 BAG65628 BC034562 AAH34562 BU195069 CK001877 HQ447960 ADQ32443 XM_011536360 XP_011534662 NM_006427 NP_006418 NM_021709 NP_068355 |
Function | Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa- B and promotes T-cell receptor-mediated apoptosis. {ECO:0000269|PubMed:12011449, ECO:0000269|PubMed:14739602, ECO:0000269|PubMed:15034012, ECO:0000269|PubMed:15958577, ECO:0000269|PubMed:16491128}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15034012}. Nucleus {ECO:0000269|PubMed:15034012}. Note=In the nucleus, accumulates in dot-like structures. |
Tissue Specificity | Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. |
SIVA1 cDNA (ANA11518) - ANA11518 from Aviva Systems Biology
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SIVA1 - MBS1268471 from MyBioSource
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Human SIVA1 cDNA clone(NM_021709.2) - CDFG003352 from Creative Biomart
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Human SIVA1 ORF Clone(NM_021709.2) - CDCR307034 from Creative Biomart
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Human SIVA1 ORF Clone(NM_021709.2) - CDCR307035 from Creative Biomart
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Human SIVA1 ORF Clone(NM_021709.2) - CDCR307036 from Creative Biomart
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Human SIVA1 ORF Clone(NM_006427.3) - CDCL175526 from Creative Biomart
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human SIVA1 ORF clone - CDCH080462 from Creative Biomart
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human SIVA1 ORF clone - CDCH080463 from Creative Biomart
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human SIVA1 ORF clone - CDCH080464 from Creative Biomart
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human SIVA1 ORF clone - CDCH080465 from Creative Biomart
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Human SIVA1 Gene ORF cDNA clone expression plasmid - HG12470-UT from Sino Biological
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Human SIVA1 ORF Clone(NM_021709.2) - CDCR307034 from Creative biogene
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Human SIVA1 ORF Clone (BC034562) - CDCS412733 from Creative biogene
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Human SIVA1 cDNA Clone(NM_021709.2) - CDFG003352 from Creative biogene
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