Gene Symbol | AZU1 |
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Entrez Gene | 566 |
Alt Symbol | AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC |
Species | Human |
Gene Type | protein-coding |
Description | azurocidin 1 |
Other Description | azurocidin|cationic antimicrobial protein 37|cationic antimicrobial protein CAP37|heparin-binding protein|neutrophil azurocidin |
Swissprots | Q9UCM1 Q52LG4 P80014 P20160 Q9UCT5 |
Accessions | AAB59353 EAW69592 P20160 BC044940 AAH44940 BC069495 AAH69495 BC093931 AAH93931 BC093933 AAH93933 HQ448471 ADQ32951 X58794 CAA41601 NM_001700 NP_001691 |
Function | This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram- negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity aga |
Subcellular Location | Cytoplasmic granule. Note=Cytoplasmic granules of neutrophils. |
Human Azurocidin full length protein - ab91129 from Abcam
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Human Azurocidin full length protein - ab152224 from Abcam
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Human Azurocidin full length protein - ab179973 from Abcam
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Human Azurocidin peptide - ab88966 from Abcam
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Human Azurocidin peptide - ab88967 from Abcam
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AZU1 / Azurocidin Antibody Blocking Peptide - LS-E3762 from LifeSpan Bioscience
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Recombinant Azurocidin/CAP37/HBP Protein - H00000566-P01 from Novus Biologicals
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AZU1-Antibody-Center-Blocking-Peptide - BP14972c from Abgent, a WuXi AppTec company
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Recombinant Human Azurocidin/CAP37/HBP - 2200-SE-050 from R&D Systems
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Recombinant Human Azurocidin/CAP37/HBP, CF - 2200-SE-050/CF from R&D Systems
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Human Azurocidin Protein (OPMA04351) - OPMA04351 from Aviva Systems Biology
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Human AZU1 His tag protein - orb82864 from Biorbyt
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Human Azurocidin protein - orb82271 from Biorbyt
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Azurocidin Protein - abx069755 from Abbexa
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Human Azurocidin 1 Protein - abx065490 from Abbexa
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Azurocidin - AR31010PU-N from Acris Antibodies
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Azurocidin - H00000566-P01 from Acris Antibodies
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Human Azurocidin - MD-27-0001P from RayBiotech
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Azurocidin - 12-7618 from ARP American Research Products
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Azurocidin 1 (AZU1), Human - 20-7730 from ARP American Research Products
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Azurocidin, Human, Recombinant - 19-C430 from ARP American Research Products
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Azurocidin Recombinant Protein - 96-038 from ProSci
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AZU1 fusion protein - ag12629 from Proteintech Group
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AZU1 fusion protein - ag12786 from Proteintech Group
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Recombinant Human CAP37 Protein - BP001228-C430 from Syd Labs
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