Gene Symbol | AZU1 |
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Entrez Gene | 566 |
Alt Symbol | AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC |
Species | Human |
Gene Type | protein-coding |
Description | azurocidin 1 |
Other Description | azurocidin|cationic antimicrobial protein 37|cationic antimicrobial protein CAP37|heparin-binding protein|neutrophil azurocidin |
Swissprots | Q9UCM1 Q52LG4 P80014 P20160 Q9UCT5 |
Accessions | AAB59353 EAW69592 P20160 BC044940 AAH44940 BC069495 AAH69495 BC093931 AAH93931 BC093933 AAH93933 HQ448471 ADQ32951 X58794 CAA41601 NM_001700 NP_001691 |
Function | This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram- negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity aga |
Subcellular Location | Cytoplasmic granule. Note=Cytoplasmic granules of neutrophils. |
azurocidin (H-70) - sc-33129 from Santa Cruz Biotechnology
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azurocidin (N-20) - sc-20293 from Santa Cruz Biotechnology
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Anti-AZU1 antibody - ab186898 from Abcam
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Anti-Azurocidin antibody - ab167336 from Abcam
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Anti-Azurocidin antibody - ab67452 from Abcam
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Anti-Azurocidin antibody - ab88819 from Abcam
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Anti-Azurocidin antibody - ab48132 from Abcam
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Anti-Azurocidin antibody (Biotin) - ab51508 from Abcam
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Anti-Azurocidin antibody [EPR9502] - ab178678 from Abcam
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Anti-Azurocidin antibody [EPR9503] - ab181989 from Abcam
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Anti-AZU1 / Azurocidin Antibody (aa23-247) - LS-C292965 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96) - LS-C156700 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa1-251) - LS-C121398 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody - LS-C74497 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, AP) - LS-C252187 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, APC) - LS-C252188 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, Biotin) - LS-C252189 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, PE) - LS-C252192 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, FITC) - LS-C252190 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96, Azide-free, HRP) - LS-C252191 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa23-247, Biotin) - LS-C297764 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa23-247, FITC) - LS-C302570 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa66-96) - LS-C319731 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody - LS-C341931 from LifeSpan Bioscience
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Anti-AZU1 / Azurocidin Antibody (aa84-133) - LS-C206196 from LifeSpan Bioscience
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