Gene Symbol | CD40LG |
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Entrez Gene | 959 |
Alt Symbol | CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L |
Species | Human |
Gene Type | protein-coding |
Description | CD40 ligand |
Other Description | CD40 antigen ligand|CD40-L|T-B cell-activating molecule|T-cell antigen Gp39|TNF-related activation protein|tumor necrosis factor (ligand) superfamily member 5 |
Swissprots | P29965 |
Accessions | AAC41932 AAZ23548 ABK41936 BAA06599 CAH25976 CAL44882 CAL99223 CAL99228 CAY55957 CBY45341 EAW88462 EAW88463 P29965 AF529195 AAQ09090 AK292637 BAF85326 AY197739 AAP37943 BC071754 AAH71754 BC074950 AAH74950 FN298241 CAX65629 HQ447532 ADQ32018 L07414 AAA35662 S66178 AAD13982 X67878 CAA48077 X68550 CAA48554 X96710 Z15017 CAA78737 NM_000074 NP_000065 |
Function | Mediates B-cell proliferation in the absence of co- stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. {ECO:0000269|PubMed:15193700}. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
Tissue Specificity | Specifically expressed on activated CD4+ T- lymphocytes. |
Top Pathways | Cytokine-cytokine receptor interaction, Primary immunodeficiency, Allograft rejection, Autoimmune thyroid disease, Intestinal immune network for IgA production |
CD154 (F-1) - sc-374635 from Santa Cruz Biotechnology
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CD154 (C-20) - sc-978 from Santa Cruz Biotechnology
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CD154 (B-4) - sc-74447 from Santa Cruz Biotechnology
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CD154 (D-19) - sc-1593 from Santa Cruz Biotechnology
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CD154 (H-215) - sc-9097 from Santa Cruz Biotechnology
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CD154 (TRAP-1) - sc-19985 from Santa Cruz Biotechnology
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CD154 (K-19) - sc-1594 from Santa Cruz Biotechnology
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CD154 (E-8) - sc-74448 from Santa Cruz Biotechnology
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Anti-CD40L antibody - ab2391 from Abcam
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Anti-CD40L antibody - ab65854 from Abcam
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Anti-CD40L antibody - ab189770 from Abcam
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Anti-CD40L antibody - ab194618 from Abcam
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Anti-CD40L antibody [24-31] - ab134403 from Abcam
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Anti-CD40L antibody [24-31] (Allophycocyanin) - ab134406 from Abcam
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Anti-CD40L antibody [24-31] (Biotin) - ab134407 from Abcam
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Anti-CD40L antibody [24-31] (FITC) - ab134404 from Abcam
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Anti-CD40L antibody [24-31] (Phycoerythrin) - ab134405 from Abcam
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Anti-CD40L antibody [24-31] - Low endotoxin, Azide free - ab171235 from Abcam
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Anti-CD40L antibody [2B10] - ab28084 from Abcam
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Anti-CD40L antibody [5F3] - ab13546 from Abcam
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Anti-CD40L antibody [B-B29] - ab47204 from Abcam
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Anti-CD40L antibody [B-B29] (FITC) - ab27407 from Abcam
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Anti-CD40L antibody [B-B29] (Phycoerythrin) - ab27408 from Abcam
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Anti-CD40L antibody (Biotin) - ab83152 from Abcam
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Anti-CD40L antibody [EP462E] - ab52750 from Abcam
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