Gene Symbol | CD40LG |
---|---|
Entrez Gene | 959 |
Alt Symbol | CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L |
Species | Human |
Gene Type | protein-coding |
Description | CD40 ligand |
Other Description | CD40 antigen ligand|CD40-L|T-B cell-activating molecule|T-cell antigen Gp39|TNF-related activation protein|tumor necrosis factor (ligand) superfamily member 5 |
Swissprots | P29965 |
Accessions | AAC41932 AAZ23548 ABK41936 BAA06599 CAH25976 CAL44882 CAL99223 CAL99228 CAY55957 CBY45341 EAW88462 EAW88463 P29965 AF529195 AAQ09090 AK292637 BAF85326 AY197739 AAP37943 BC071754 AAH71754 BC074950 AAH74950 FN298241 CAX65629 HQ447532 ADQ32018 L07414 AAA35662 S66178 AAD13982 X67878 CAA48077 X68550 CAA48554 X96710 Z15017 CAA78737 NM_000074 NP_000065 |
Function | Mediates B-cell proliferation in the absence of co- stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. {ECO:0000269|PubMed:15193700}. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
Tissue Specificity | Specifically expressed on activated CD4+ T- lymphocytes. |
Top Pathways | Cytokine-cytokine receptor interaction, Primary immunodeficiency, Allograft rejection, Autoimmune thyroid disease, Intestinal immune network for IgA production |
Active human CD40L full length protein - ab173999 from Abcam
|
||||||||||
Active human CD40L full length protein - ab191775 from Abcam
|
||||||||||
Active human CD40L protein fragment - ab168061 from Abcam
|
||||||||||
Active human CD40L protein fragment - ab179625 from Abcam
|
||||||||||
Active human CD40L protein fragment - ab51956 from Abcam
|
||||||||||
Active mouse CD40L full length protein - ab50160 from Abcam
|
||||||||||
Horse CD40L protein fragment - ab203557 from Abcam
|
||||||||||
Human CD40L full length protein - ab119150 from Abcam
|
||||||||||
Human CD40L full length protein - ab105610 from Abcam
|
||||||||||
Human CD40L full length protein - ab194154 from Abcam
|
||||||||||
Human IgM full length protein - ab90348 from Abcam
|
||||||||||
Human IgM full length protein - ab158748 from Abcam
|
||||||||||
IgM mu chain, Human Plasma - ab91106 from Abcam
|
||||||||||
Human IgM full length protein - ab91117 from Abcam
|
||||||||||
CD40L Antibody Blocking Peptide - LS-E11965 from LifeSpan Bioscience
|
||||||||||
CD40L Antibody Blocking Peptide - LS-E8276 from LifeSpan Bioscience
|
||||||||||
CD40L Antibody Blocking Peptide - LS-E8275 from LifeSpan Bioscience
|
||||||||||
TRAF2 Antibody Blocking Peptide - LS-E30198 from LifeSpan Bioscience
|
||||||||||
TRAF2 Antibody Blocking Peptide - LS-E30199 from LifeSpan Bioscience
|
||||||||||
TRAF2 Antibody Blocking Peptide - LS-E26060 from LifeSpan Bioscience
|
||||||||||
TRAF2 Antibody Blocking Peptide - LS-E9292 from LifeSpan Bioscience
|
||||||||||
Recombinant Human CD40 Ligand/TNFSF5 Protein - NBP2-35244 from Novus Biologicals
|
||||||||||
CD40 Ligand/TNFSF5 Partial Recombinant Protein - H00000959-Q01 from Novus Biologicals
|
||||||||||
Human IgM Fab Mu Full length Protein - NBP1-97053 from Novus Biologicals
|
||||||||||
CD40 Ligand/TNFSF5 Recombinant Protein - H00000959-P01 from Novus Biologicals
|