Gene Symbol | ZIC3 |
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Entrez Gene | 7547 |
Alt Symbol | HTX, HTX1, VACTERLX, ZNF203 |
Species | Human |
Gene Type | protein-coding |
Description | Zic family member 3 |
Other Description | Zic family member 3 (odd-paired homolog, Drosophila)|heterotaxy 1|zinc finger protein 203|zinc finger protein ZIC 3|zinc finger protein of the cerebellum 3 |
Swissprots | Q5JY75 Q14DE5 B2CNW4 O60481 |
Accessions | EAW88447 O60481 AF028706 AAC05594 BC111854 AAI11855 BC113393 AAI13394 BC113395 AAI13396 BM667189 EU532020 ACB30403 HQ258447 ADR83201 NM_003413 NP_003404 |
Function | Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. {ECO:0000269|PubMed:17764085}. |
Subcellular Location | Nucleus. Cytoplasm {ECO:0000250}. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6. {ECO:0000250}. |
Top Pathways | Signaling pathways regulating pluripotency of stem cells |
Human ZIC3 full length protein - ab159826 from Abcam
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Human ZIC3 protein fragment - ab159827 from Abcam
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ZIC3 Antibody Blocking Peptide - LS-E27644 from LifeSpan Bioscience
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ZIC3 Antibody Blocking Peptide - LS-E27645 from LifeSpan Bioscience
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ZIC3 Antibody Blocking Peptide - LS-E7079 from LifeSpan Bioscience
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ZIC3 Antibody Blocking Peptide - LS-E11839 from LifeSpan Bioscience
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Recombinant Human ZIC3 Protein - H00007547-Q01 from Novus Biologicals
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Recombinant Human ZIC3 Protein - H00007547-P01 from Novus Biologicals
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ZIC3 Peptide - P1253 from Novus Biologicals
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ZIC3-Antibody-N-term-Blocking-Peptide - BP2761a from Abgent, a WuXi AppTec company
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ZIC3 Immunizing peptide - orb66339 from Biorbyt
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ZIC3 Peptide - AC21-2462-P from Abcore
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ZIC3 Peptide - AC21-2463-P from Abcore
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ZIC3 - H00007547-P01-10 from Acris Antibodies
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ZIC3 - H00007547-P01-25 from Acris Antibodies
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ZIC3 - H00007547-Q01-10 from Acris Antibodies
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ZIC3 - H00007547-Q01-25 from Acris Antibodies
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ZIC3 Peptide - 42-974P from ProSci
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ZIC3 Peptide - 42-973P from ProSci
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ZIC3 fusion protein - ag16354 from Proteintech Group
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ZIC3 fusion protein - ag18083 from Proteintech Group
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Recombinant Human Zinc finger protein ZIC 3(ZIC3) - CSB-YP026486HU CSB-EP026486HU CSB-BP026486HU CSB-MP026486HU from Cusabio
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ZIC3 (N-term HIS tag) - TP760426 from Acris Antibodies
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Zinc finger protein ZIC 3(ZIC3) , Recombinant Protein - MBS1073232 from MyBioSource
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ZIC3, Peptide - MBS427527 from MyBioSource
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