ZIC3

Gene Symbol ZIC3
Entrez Gene 7547
Alt Symbol HTX, HTX1, VACTERLX, ZNF203
Species Human
Gene Type protein-coding
Description Zic family member 3
Other Description Zic family member 3 (odd-paired homolog, Drosophila)|heterotaxy 1|zinc finger protein 203|zinc finger protein ZIC 3|zinc finger protein of the cerebellum 3
Swissprots Q5JY75 Q14DE5 B2CNW4 O60481
Accessions EAW88447 O60481 AF028706 AAC05594 BC111854 AAI11855 BC113393 AAI13394 BC113395 AAI13396 BM667189 EU532020 ACB30403 HQ258447 ADR83201 NM_003413 NP_003404
Function Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'. {ECO:0000269|PubMed:17764085}.
Subcellular Location Nucleus. Cytoplasm {ECO:0000250}. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6. {ECO:0000250}.
Top Pathways Signaling pathways regulating pluripotency of stem cells

Zic3 CRISPR/Cas9 KO Plasmid (h) - sc-407048 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 HDR Plasmid (h) - sc-407048-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 Double Nickase Plasmid (h) - sc-407048-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 Double Nickase Plasmid (h2) - sc-407048-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 CRISPR Activation Plasmid (h) - sc-407048-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 CRISPR Activation Plasmid (h2) - sc-407048-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 Lentiviral Activation Particles (h) - sc-407048-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 Lentiviral Activation Particles (h2) - sc-407048-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Zic3 siRNA (h) - sc-106711 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Zic3 shRNA Plasmid (h) - sc-106711-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Zic3 shRNA (h) Lentiviral Particles - sc-106711-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZIC3 RNAi - H00007547-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU042201 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23220 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23220 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10966 from Sigma-Aldrich

Category miRNA

ZIC3 siRNA (Human) - CRH5158 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZIC3 - MBS8204105 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZIC3 (NM_003413.3) - SHH452648 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZIC3 siRNA - orb265660 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZIC3 shRNA Plasmid (Human) - CHH5158 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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