LPCAT1

Gene Symbol LPCAT1
Entrez Gene 79888
Alt Symbol AYTL2, PFAAP3, lpcat
Species Human
Gene Type protein-coding
Description lysophosphatidylcholine acyltransferase 1
Other Description 1-acylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|LPC acyltransferase 1|LPCAT-1|acetyl-CoA:lyso-PAF acetyltransferase|acetyl-CoA:lyso-platelet-activating factor acetyltransferase|acyl-CoA:lysophosphatidylcholine acyltransferase 1|acyltransferase like 2|acyltransferase-like 2|lyso-PAF acetyltransferase|lysoPAFAT|lysoPC acyltransferase 1|phosphonoformate immuno-associated protein 3|regulated by phosphonoformate
Swissprots Q8NF37 Q1HAQ1 Q9GZW6 Q7Z4G6 Q8WUL8 Q8N3U7
Accessions EAX08154 EAX08155 EAX08156 Q8NF37 AB244719 BAE94688 AF052162 AF530061 AAQ09945 AK022499 BAB14061 AK022505 BAB14065 AK090444 BAC03425 AK095552 AK123603 AL831864 CAD38556 BC002543 BC020166 AAH20166 BC140367 AAI40368 BQ961819 BU539058 XM_005248373 XP_005248430 XM_011514132 XP_011512434 XM_011514133 XP_011512435 XM_011514134 XP_011512436 NM_024830 NP_079106
Function Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. {ECO:0000269|PubMed:16864775, ECO:0000269|PubMed:21498505}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Golgi apparatus membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Lipid droplet {ECO:0000269|PubMed:21498505}. Note=May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm.
Top Pathways Ether lipid metabolism, Glycerophospholipid metabolism

LPCAT1 - MBS1273547 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC020166

Human LPCAT1 cDNA clone(NM_024830.3) - CDFG004703 from Creative Biomart

Species Human
Accession NM_024830.3

Human LPCAT1 ORF Clone(NM_024830.3) - CDCR309671 from Creative Biomart

Species Human
Accession NM_024830.3

Human LPCAT1 ORF Clone(NM_024830.3) - CDCR309672 from Creative Biomart

Species Human
Accession NM_024830.3

Human LPCAT1 ORF Clone(NM_024830.3) - CDCL169059 from Creative Biomart

Species Human
Accession NM_024830.3

Human LPCAT1 Gene cDNA Clone (full-length ORF Clone) - HG16470-G from Sino Biological

Species Human
Accession NM_024830.3

Human LPCAT1 natural ORF mammalian expression plasmid - HG16470-UT from Sino Biological

Species Human
Accession NM_024830.3

Human LPCAT1 natural ORF mammalian expression plasmid, C-His tag - HG16470-CH from Sino Biological

Species Human
Accession NM_024830.3

Human LPCAT1 natural ORF mammalian expression plasmid, N-Flag tag - HG16470-NF from Sino Biological

Species Human
Accession NM_024830.3

Mouse LPCAT1 ORF clone (NM_024830.3) - CDCL128153 from Creative biogene

Species Human

Human LPCAT1 ORF Clone (BC020166) - CDCS415837 from Creative biogene

Species Human
Accession Q8NF37

Human LPCAT1 cDNA Clone(NM_024830.3) - CDFG004703 from Creative biogene

Species Human
Search more