LPCAT1

Gene Symbol	LPCAT1
Entrez Gene	79888
Alt Symbol	AYTL2, PFAAP3, lpcat
Species	Human
Gene Type	protein-coding
Description	lysophosphatidylcholine acyltransferase 1
Other Description	1-acylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|LPC acyltransferase 1|LPCAT-1|acetyl-CoA:lyso-PAF acetyltransferase|acetyl-CoA:lyso-platelet-activating factor acetyltransferase|acyl-CoA:lysophosphatidylcholine acyltransferase 1|acyltransferase like 2|acyltransferase-like 2|lyso-PAF acetyltransferase|lysoPAFAT|lysoPC acyltransferase 1|phosphonoformate immuno-associated protein 3|regulated by phosphonoformate
Swissprots	Q8NF37 Q1HAQ1 Q9GZW6 Q7Z4G6 Q8WUL8 Q8N3U7
Accessions	EAX08154 EAX08155 EAX08156 Q8NF37 AB244719 BAE94688 AF052162 AF530061 AAQ09945 AK022499 BAB14061 AK022505 BAB14065 AK090444 BAC03425 AK095552 AK123603 AL831864 CAD38556 BC002543 BC020166 AAH20166 BC140367 AAI40368 BQ961819 BU539058 XM_005248373 XP_005248430 XM_011514132 XP_011512434 XM_011514133 XP_011512435 XM_011514134 XP_011512436 NM_024830 NP_079106
Function	Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology. {ECO:0000269|PubMed:16864775, ECO:0000269|PubMed:21498505}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Golgi apparatus membrane {ECO:0000269|PubMed:21498505}; Single-pass type II membrane protein {ECO:0000269|PubMed:21498505}. Lipid droplet {ECO:0000269|PubMed:21498505}. Note=May adopt a monotopic topology when embedded in the lipid monolayer of the lipid droplet, with both termini exposed to the cytoplasm.
Top Pathways	Ether lipid metabolism, Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LPCAT1 protein fragment - ab140540 from Abcam Category Protein Source E. coli Species Human

LPCAT1 / AYTL2 Antibody Blocking Peptide - LS-E18018 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LPCAT1 / AYTL2 Antibody Blocking Peptide - LS-E10058 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

LPCAT1 / AYTL2 Antibody Blocking Peptide - LS-E29805 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

LPCAT1 / AYTL2 Antibody Blocking Peptide - LS-E29806 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human LPCAT1 Protein - NBP2-23206 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

PCAT1-Antibody-C-term-Blocking-Peptide - BP9310b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human LPCAT1 protein - orb191398 from Biorbyt Category Protein Prices $170.00, $289.00, $1,139.00 Sizes 2 μg, 10 μg, 100 μg Source Escherichia Coli. Species Human

LPCAT1 Blocking Peptide - 33R-5370 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

LPCAT1 protein (His tag) - 80R-2716 from Fitzgerald Category Protein Prices $270.00 Sizes 20 µg Source E.coli

LPCAT1 (79-534, His-tag) - AR50836PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

LPCAT1 (79-534, His-tag) - AR50836PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

LPCAT1, 79-534aa, Human, His tag, E.coli - 01-P2012 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

LPCAT1 fusion protein - Ag9035 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

LPCAT1 fusion protein - Ag9060 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human LPCAT1, His-tagged - LPCAT1-7568H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human LPCAT1, GST-tagged - LPCAT1-620H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) - RPG529Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) - RPG529Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) - RPG529Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) - RPG529Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Lysophosphatidylcholine acyltransferase 1(LPCAT1) - CSB-YP013052HU CSB-EP013052HU CSB-BP013052HU CSB-MP013052HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

LPCAT1, 79-534aa, Human, His tag, E.coli (Denatured) - ATGP2012 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

Lysophosphatidylcholine Acyltransferase 1 Protein (Recombinant) - abx168194 from Abbexa Category Protein Source Human Species Human

LPCAT1 - TP320083 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

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