Gene Symbol | CITED1 |
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Entrez Gene | 4435 |
Alt Symbol | MSG1 |
Species | Human |
Gene Type | protein-coding |
Description | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
Other Description | cbp/p300-interacting transactivator 1|melanocyte-specific gene 1|melanocyte-specific protein 1 |
Swissprots | B5BUI2 B5BU50 Q99966 |
Accessions | EAW71818 EAW71819 EAW71820 Q99966 AB451286 BAG70100 AB451418 BAG70232 AI217516 BC004240 AAH04240 BP247232 DQ892984 ABM83910 DQ896232 ABM87231 N27803 U65092 AAC51113 XM_011530958 XP_011529260 NM_001144885 NP_001138357 NM_001144886 NP_001138358 NM_001144887 NP_001138359 NM_004143 NP_004134 |
Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16864582}. Cytoplasm {ECO:0000269|PubMed:16864582}. Note=Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner. |
Tissue Specificity | Expressed only in melanocytes and testis. |
MSG1 (K-12) - sc-50743 from Santa Cruz Biotechnology
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MSG1 (N-17) - sc-50744 from Santa Cruz Biotechnology
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MSG1 (35-W) - sc-101002 from Santa Cruz Biotechnology
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Anti-CITED1 antibody - ab55467 from Abcam
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Anti-CITED1 Antibody (aa94-194, clone 10B2246, Azide-free) - LS-C183518 from LifeSpan Bioscience
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Anti-CITED1 Antibody - LS-C311055 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 1E11) - LS-C340176 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 2H7) - LS-C340148 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 3B1) - LS-C340177 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 1C6) - LS-C340169 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 4H4) - LS-C340179 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 3C12) - LS-C340183 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 3B8) - LS-C340196 from LifeSpan Bioscience
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Anti-CITED1 Antibody (clone 5H6) - LS-C133330 from LifeSpan Bioscience
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Anti-CITED1 Antibody (aa69-118) IHC-plus™ - LS-B11874 from LifeSpan Bioscience
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CITED1 Antibody (5H6) - H00004435-M03 from Novus Biologicals
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CITED1 Antibody (6G8) - H00004435-M01 from Novus Biologicals
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CITED1 Antibody (6C8) - H00004435-M05 from Novus Biologicals
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CITED1 Antibody (6C1) - H00004435-M02 from Novus Biologicals
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CITED1 Antibody (6E12.) - H00004435-M04 from Novus Biologicals
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CITED1 Antibody (2H6) - H00004435-M06 from Novus Biologicals
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CITED1 Antibody - H00004435-D01 from Novus Biologicals
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CITED1 Antibody - H00004435-A01 from Novus Biologicals
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CITED1 Polyclonal Antibody - bs-2990R from Bioss
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Monoclonal Anti-CITED1 antibody produced in mouse - SAB1409326 from Sigma-Aldrich
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