CITED1

Gene Symbol	CITED1
Entrez Gene	4435
Alt Symbol	MSG1
Species	Human
Gene Type	protein-coding
Description	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
Other Description	cbp/p300-interacting transactivator 1|melanocyte-specific gene 1|melanocyte-specific protein 1
Swissprots	B5BUI2 B5BU50 Q99966
Accessions	EAW71818 EAW71819 EAW71820 Q99966 AB451286 BAG70100 AB451418 BAG70232 AI217516 BC004240 AAH04240 BP247232 DQ892984 ABM83910 DQ896232 ABM87231 N27803 U65092 AAC51113 XM_011530958 XP_011529260 NM_001144885 NP_001138357 NM_001144886 NP_001138358 NM_001144887 NP_001138359 NM_004143 NP_004134
Function	Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a
Subcellular Location	Nucleus {ECO:0000269|PubMed:16864582}. Cytoplasm {ECO:0000269|PubMed:16864582}. Note=Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner.
Tissue Specificity	Expressed only in melanocytes and testis.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CITED1 overexpression lysate - LY418187 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CITED1 overexpression lysate - LY428546 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CITED1 overexpression lysate - LY428547 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CITED1 293 Cell Lysate - 408486 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CITED1 Overexpression Lysate (Native) - NBL1-09217 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CITED1 Over-expression Lysate Product - GWB-F22720 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CITED1 Overexpression Lysate (Native) - NBP2-09714 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CITED1 Overexpression Lysate (Native) - NBP2-09713 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human CITED1 Knockdown Stable Cell Line - CSC-DC003188 from Creative biogene Category Cell Line Species Human

Human CITED1 Knockout Cell Line-HEK293T - CSC-RT0667 from Creative biogene Category Cell Line Species Human

CITED1 KO Cell Lysate-HEK293T - CLKO-0173 from Creative biogene Category Cell Lysate

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