Gene Symbol | CITED1 |
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Entrez Gene | 4435 |
Alt Symbol | MSG1 |
Species | Human |
Gene Type | protein-coding |
Description | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
Other Description | cbp/p300-interacting transactivator 1|melanocyte-specific gene 1|melanocyte-specific protein 1 |
Swissprots | B5BUI2 B5BU50 Q99966 |
Accessions | EAW71818 EAW71819 EAW71820 Q99966 AB451286 BAG70100 AB451418 BAG70232 AI217516 BC004240 AAH04240 BP247232 DQ892984 ABM83910 DQ896232 ABM87231 N27803 U65092 AAC51113 XM_011530958 XP_011529260 NM_001144885 NP_001138357 NM_001144886 NP_001138358 NM_001144887 NP_001138359 NM_004143 NP_004134 |
Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a |
Subcellular Location | Nucleus {ECO:0000269|PubMed:16864582}. Cytoplasm {ECO:0000269|PubMed:16864582}. Note=Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner. |
Tissue Specificity | Expressed only in melanocytes and testis. |
Human CITED1 full length protein - ab152540 from Abcam
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Human CITED1 protein fragment - ab152541 from Abcam
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CITED1 Antibody Blocking Peptide - LS-E11494 from LifeSpan Bioscience
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Recombinant Human CITED1 Protein - H00004435-Q01 from Novus Biologicals
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Recombinant Human CITED1 Protein - H00004435-P01 from Novus Biologicals
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MAPT Protein (OPPA01212) - OPPA01212 from Aviva Systems Biology
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CITED1 - H00004435-P01-02 from Acris Antibodies
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CITED1 - H00004435-Q01-10 from Acris Antibodies
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CITED1 - H00004435-Q01-25 from Acris Antibodies
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CITED1 fusion protein - ag0745 from Proteintech Group
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CITED1 Human - GWB-D37D4F from Genway Biotech
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Recombinant Human CITED1 - CITED1-1276H from Creative Biomart
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Recombinant Cbp/p300 Interacting Transactivator, With Glu/Asp Rich Carboxy Terminal Domain 1 (CITED1) - RPJ771Hu01 from Uscn Life Science Inc.
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Recombinant Cbp/p300 Interacting Transactivator, With Glu/Asp Rich Carboxy Terminal Domain 1 (CITED1) - RPJ771Mu01 from Uscn Life Science Inc.
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Recombinant Cbp/p300 Interacting Transactivator, With Glu/Asp Rich Carboxy Terminal Domain 1 (CITED1) - RPJ771Hu01 from Cloud-clone
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Recombinant Human Cbp/p300-interacting transactivator 1(CITED1) - CSB-YP858732HU CSB-EP858732HU CSB-BP858732HU CSB-MP858732HU from Cusabio
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CITED1 (transcript variant 1) - TP302419 from Acris Antibodies
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CITED1 (transcript variant 3) - TP327378 from Acris Antibodies
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CITED1 (transcript variant 4) - TP327383 from Acris Antibodies
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Cbp/p300-interacting transactivator 1 (CITED1), Recombinant Protein - MBS1444868 from MyBioSource
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Recombinant Human CITED1 - CRC131A from Cell Science
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Recombinant Human CITED1 - CRC131B from Cell Science
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Recombinant Human CITED1 - CRC131C from Cell Science
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CITED1 Peptide, Human - M34GP03188H from Creative Peptides
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CITED1 fusion protein - Ag24633 from Proteintech Group
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