Gene Symbol | CMTR2 |
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Entrez Gene | 55783 |
Alt Symbol | AFT, FTSJD1, HMTr2, MTr2 |
Species | Human |
Gene Type | protein-coding |
Description | cap methyltransferase 2 |
Other Description | FtsJ methyltransferase domain containing 1|adrift homolog|cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2|cap2 2'O-ribose methyltransferase 2|ftsJ methyltransferase domain-containing protein 1|protein adrift homolog |
Swissprots | Q9NXF5 Q8NE77 Q9H8Z4 Q8IYT2 Q9NUS3 Q8NFR5 B2RCD5 D3DWS1 |
Accessions | EAW59246 EAW59247 Q8IYT2 AA968997 AF458590 AAM49718 AK000289 BAA91058 AK002033 BAA92047 AK023183 BAB14452 AK123343 AK226169 AK315056 BAG37532 BC034468 AAH34468 BC035005 AAH35005 BX648660 DB227997 DB240113 XM_005256046 XP_005256103 XM_005256047 XP_005256104 XM_011523228 XP_011521530 XM_011523229 XP_011521531 NM_001099642 NP_001093112 NM_018348 NP_060818 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs. {ECO:0000269|PubMed:21310715}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:21310715}. Cytoplasm {ECO:0000269|PubMed:21310715}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Anti-FTSJD1 antibody - ab105698 from Abcam
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Anti-FTSJD1 antibody - ab105699 from Abcam
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Anti-FTSJD1 antibody - ab184824 from Abcam
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Anti-CMTR2 / FTSJD1 Antibody (aa287-336) - LS-C112002 from LifeSpan Bioscience
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Anti-CMTR2 / FTSJD1 Antibody (aa431-480) - LS-C112003 from LifeSpan Bioscience
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FTSJ1 Antibody - NBP1-52940 from Novus Biologicals
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FTSJD1 Antibody - NBP1-70751 from Novus Biologicals
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FTSJD1 Antibody - NBP2-30516 from Novus Biologicals
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FTSJD1 Antibody - NBP2-30944 from Novus Biologicals
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Anti-FTSJD1 antibody produced in rabbit - HPA048265 from Sigma-Aldrich
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Anti-FTSJD1 antibody produced in rabbit - SAB2106071 from Sigma-Aldrich
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Anti-FTSJD1 antibody produced in rabbit - SAB2106072 from Sigma-Aldrich
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Anti-FTSJD1 antibody produced in rabbit - HPA041700 from Sigma-Aldrich
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FTSJD1 antibody - middle region (ARP57215_P050) - ARP57215_P050 from Aviva Systems Biology
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FTSJD1 antibody - middle region (ARP57216_P050) - ARP57216_P050 from Aviva Systems Biology
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FTSJD1 antibody [N1N2], N-term - GTX106660 from GeneTex
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FTSJD1 antibody, Internal - GTX44951 from GeneTex
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FTSJD1 antibody, Internal - GTX44952 from GeneTex
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FTSJD1 antibody - 70R-3874 from Fitzgerald
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FTSJD1 antibody - 70R-4076 from Fitzgerald
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FTSJD1 antibody - H00055783-B01P from Acris Antibodies
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FTSJD1 Antibody - GWB-MU732C from Genway Biotech
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FTSJD1 Antibody - GWB-MU733D from Genway Biotech
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Anti-FTSJD1 (aa 325-421) polyclonal antibody - DPABH-14651 from Creative Diagnostics
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AFT mAb 1, Monoclonal Antibody - MBS478101 from MyBioSource
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