MED21

Gene Symbol MED21
Entrez Gene 9412
Alt Symbol SRB7, SURB7, hSrb7
Species Human
Gene Type protein-coding
Description mediator complex subunit 21
Other Description RNA polymerase II holoenzyme component SRB7|RNAPII complex component SRB7|SRB7 suppressor of RNA polymerase B homolog|mediator of RNA polymerase II transcription subunit 21
Swissprots Q92811 Q6IB05 Q13503 B2R4I3
Accessions EAW96544 EAW96545 EAW96546 EAW96547 Q13503 AK309064 AK311838 BAG34780 BC008380 AAH08380 CR456999 CAG33280 DA420057 DB024509 EU446930 ABZ92459 HY075642 U46837 AAA98511 U52960 AAB06944 NM_001271811 NP_001258740 NM_004264 NP_004255 NR_073463 NR_073464
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15249124, ECO:0000269|PubMed:9660976}.
Subcellular Location Nucleus {ECO:0000305}.

Srb7 CRISPR/Cas9 KO Plasmid (h) - sc-407935 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 HDR Plasmid (h) - sc-407935-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 Double Nickase Plasmid (h) - sc-407935-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 Double Nickase Plasmid (h2) - sc-407935-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 CRISPR Activation Plasmid (h) - sc-407935-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 CRISPR Activation Plasmid (h2) - sc-407935-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 Lentiviral Activation Particles (h) - sc-407935-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 Lentiviral Activation Particles (h2) - sc-407935-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Srb7 siRNA (h) - sc-38585 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Srb7 shRNA Plasmid (h) - sc-38585-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Srb7 shRNA (h) Lentiviral Particles - sc-38585-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MED21 RNAi - H00009412-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU132311 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN13170 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13170 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08935 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08935

MED21 siRNA (Human) - CRH6240 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MED21 (NM_004264.3) - SHH339987 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SURB7(NM_004264.3) - SHH222540 from Creative biogene

Category siRNA
Species Reactivities Human

Human MED21 siRNA - orb266742 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MED21 shRNA Plasmid (Human) - CHH6240 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MED21 miRNA 3'UTR clone - MiUTR1H-10074 from Creative biogene

Species Reactivities Human
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