TRAIP

Gene Symbol	TRAIP
Entrez Gene	10293
Alt Symbol	RNF206, TRIP
Species	Human
Gene Type	protein-coding
Description	TRAF interacting protein
Other Description	E3 ubiquitin-protein ligase TRAIP|TRAF-interacting protein|ring finger protein 206
Swissprots	O00467 B5BU84 Q9BWF2 B5BUL3
Accessions	EAW65025 EAW65026 Q9BWF2 AB451320 BAG70134 AB451449 BAG70263 AK225873 AK292172 BAF84861 AK295780 BAG58603 BC000310 AAH00310 BC019283 AAH19283 BQ446539 BX473682 EF036504 ABO65090 HQ448174 ADQ32655 U77845 AAB52993 XM_011533264 XP_011531566 XR_940361 NM_005879 NP_005870
Function	Inhibits activation of NF-kappa-B mediated by TNF (By similarity). Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFN-beta production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation. May mediate assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN to facilitate bypass of DNA lesions and preserve genomic integrity. {ECO:0000250, ECO:0000269|PubMed:22945920, ECO:0000269|PubMed:24553286}.
Subcellular Location	Cytoplasm. Cytoplasm, perinuclear region. Nucleus, nucleolus. Note=Occasionally observed at nuclear puncta.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TRAIP-cDNA-Clone - DC00135 from Abgent, a WuXi AppTec company Prices $633.15 Sizes 10 µg Species Human Accession BC000310

TRAIP - MBS1275597 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000310

Human TRAIP cDNA clone(NM_005879.2) - CDFH020270 from Creative Biomart Species Human Accession NM_005879.2

Human TRAIP ORF Clone(NM_005879.2) - CDCL179506 from Creative Biomart Species Human Accession NM_005879.2

Human TRAIP ORF Clone(NM_005879.2) - CDCR291514 from Creative Biomart Species Human Accession NM_005879.2

Human TRAIP ORF Clone(NM_005879.2) - CDCR291515 from Creative Biomart Species Human Accession NM_005879.2

Human TRAIP ORF Clone(NM_005879.2) - CDCR291516 from Creative Biomart Species Human Accession NM_005879.2

human TRAIP ORF clone - CDCH094554 from Creative Biomart Species Human Accession NM_005879

human TRAIP ORF clone - CDCH094555 from Creative Biomart Species Human Accession NM_005879

human TRAIP ORF clone - CDCH094556 from Creative Biomart Species Human Accession NM_005879

human TRAIP ORF clone - CDCH094557 from Creative Biomart Species Human Accession NM_005879

Human TRAIP Gene ORF cDNA clone in cloning vector - HG15554-G from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-His tag - HG15554-CH from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-HA tag - HG15554-CY from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15554-NF from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15554-CF from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15554-NM from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15554-CM from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-HA tag - HG15554-NY from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15554-ACG from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15554-ANG from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid - HG15554-UT from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15554-ACR from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15554-ANR from Sino Biological Species Human

Human TRAIP Gene ORF cDNA clone expression plasmid, N-His tag - HG15554-NH from Sino Biological Species Human

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