TRAIP

Gene Symbol TRAIP
Entrez Gene 10293
Alt Symbol RNF206, TRIP
Species Human
Gene Type protein-coding
Description TRAF interacting protein
Other Description E3 ubiquitin-protein ligase TRAIP|TRAF-interacting protein|ring finger protein 206
Swissprots O00467 B5BU84 Q9BWF2 B5BUL3
Accessions EAW65025 EAW65026 Q9BWF2 AB451320 BAG70134 AB451449 BAG70263 AK225873 AK292172 BAF84861 AK295780 BAG58603 BC000310 AAH00310 BC019283 AAH19283 BQ446539 BX473682 EF036504 ABO65090 HQ448174 ADQ32655 U77845 AAB52993 XM_011533264 XP_011531566 XR_940361 NM_005879 NP_005870
Function Inhibits activation of NF-kappa-B mediated by TNF (By similarity). Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFN-beta production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation. May mediate assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN to facilitate bypass of DNA lesions and preserve genomic integrity. {ECO:0000250, ECO:0000269|PubMed:22945920, ECO:0000269|PubMed:24553286}.
Subcellular Location Cytoplasm. Cytoplasm, perinuclear region. Nucleus, nucleolus. Note=Occasionally observed at nuclear puncta.

TRIP CRISPR/Cas9 KO Plasmid (h) - sc-411450 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP HDR Plasmid (h) - sc-411450-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP Double Nickase Plasmid (h) - sc-411450-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP Double Nickase Plasmid (h2) - sc-411450-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP CRISPR Activation Plasmid (h) - sc-411450-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP CRISPR Activation Plasmid (h2) - sc-411450-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP Lentiviral Activation Particles (h) - sc-411450-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP Lentiviral Activation Particles (h2) - sc-411450-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TRIP siRNA (h) - sc-78032 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIP shRNA Plasmid (h) - sc-78032-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRIP shRNA (h) Lentiviral Particles - sc-78032-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TRAIP RNAi - H00010293-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21913 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21913 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04663 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04663

TRAIP siRNA (Human) - CRH6973 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TRAIP - MBS8202078 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TRAIP (NM_005879.2) - SHH433808 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human TRAIP(NM_005879.2) - SHL091350 from Creative biogene

Category siRNA
Species Reactivities Human

TRAIP shRNA Plasmid (Human) - CHH6973 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TRAIP miRNA 3'UTR clone - MiUTR1H-10698 from Creative biogene

Species Reactivities Human
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