Gene Symbol | TRAIP |
---|---|
Entrez Gene | 10293 |
Alt Symbol | RNF206, TRIP |
Species | Human |
Gene Type | protein-coding |
Description | TRAF interacting protein |
Other Description | E3 ubiquitin-protein ligase TRAIP|TRAF-interacting protein|ring finger protein 206 |
Swissprots | O00467 B5BU84 Q9BWF2 B5BUL3 |
Accessions | EAW65025 EAW65026 Q9BWF2 AB451320 BAG70134 AB451449 BAG70263 AK225873 AK292172 BAF84861 AK295780 BAG58603 BC000310 AAH00310 BC019283 AAH19283 BQ446539 BX473682 EF036504 ABO65090 HQ448174 ADQ32655 U77845 AAB52993 XM_011533264 XP_011531566 XR_940361 NM_005879 NP_005870 |
Function | Inhibits activation of NF-kappa-B mediated by TNF (By similarity). Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFN-beta production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation. May mediate assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN to facilitate bypass of DNA lesions and preserve genomic integrity. {ECO:0000250, ECO:0000269|PubMed:22945920, ECO:0000269|PubMed:24553286}. |
Subcellular Location | Cytoplasm. Cytoplasm, perinuclear region. Nucleus, nucleolus. Note=Occasionally observed at nuclear puncta. |
Human TRIP full length protein - ab75648 from Abcam
|
||||||||||
TRAIP / TRIP Antibody Blocking Peptide - LS-E25539 from LifeSpan Bioscience
|
||||||||||
TRAIP / TRIP Antibody Blocking Peptide - LS-E7124 from LifeSpan Bioscience
|
||||||||||
TRIP / LRRFIP1 Antibody Blocking Peptide - LS-E18270 from LifeSpan Bioscience
|
||||||||||
TRIP / LRRFIP1 Antibody Blocking Peptide - LS-E31087 from LifeSpan Bioscience
|
||||||||||
TRIP / LRRFIP1 Antibody Blocking Peptide - LS-E13844 from LifeSpan Bioscience
|
||||||||||
TRIP / LRRFIP1 Antibody Blocking Peptide - LS-E21593 from LifeSpan Bioscience
|
||||||||||
TRIP / LRRFIP1 Antibody Blocking Peptide - LS-E12703 from LifeSpan Bioscience
|
||||||||||
TRAIP Partial Recombinant Protein - H00010293-Q01 from Novus Biologicals
|
||||||||||
TRAIP-Antibody-C-term-Blocking-Peptide - BP2820b from Abgent, a WuXi AppTec company
|
||||||||||
TRIP blocking peptide - GTX24533-PEP from GeneTex
|
||||||||||
TRIP Peptide - AC21-0368-P from Abcore
|
||||||||||
TRAIP / RNF206 - H00010293-Q01-10 from Acris Antibodies
|
||||||||||
TRAIP / RNF206 - H00010293-Q01-25 from Acris Antibodies
|
||||||||||
TRIP Peptide - 46-529P from ProSci
|
||||||||||
TRAIP fusion protein - ag0491 from Proteintech Group
|
||||||||||
Recombinant Human TRAIP - TRAIP-31614TH from Creative Biomart
|
||||||||||
Recombinant Human TRAF-interacting protein(TRAIP) - CSB-YP866296HU CSB-EP866296HU CSB-BP866296HU CSB-MP866296HU from Cusabio
|
||||||||||
TRIP/TRAIP, Peptide - MBS426935 from MyBioSource
|
||||||||||
TRAIP Recombinant Protein Antigen - NBP1-87125PEP from Novus Biologicals
|
||||||||||
TRAIP Recombinant Protein Antigen - NBP2-48655PEP from Novus Biologicals
|
||||||||||
TRAIP Peptide, Human - M34GP16523H from Creative Peptides
|
||||||||||
TRAIP Immunizing peptide - orb17098 from Biorbyt
|