DCUN1D1

Gene Symbol DCUN1D1
Entrez Gene 54165
Alt Symbol DCNL1, DCUN1L1, RP42, SCCRO, SCRO, Tes3
Species Human
Gene Type protein-coding
Description DCN1, defective in cullin neddylation 1, domain containing 1
Other Description DCN1-like protein 1|DCUN1 domain-containing protein 1|RP42 homolog|defective in cullin neddylation protein 1-like protein 1|squamous cell carcinoma related oncogene|squamous cell carcinoma-related oncogene
Swissprots Q9HCT3 Q8TEX7 Q9H6M1 Q7L3G9 Q96GG9 B2RB37
Accessions CAJ01275 CAJ42719 CCA61624 CDM22108 EAW78341 EAW78342 EAW78343 Q96GG9 AF292100 AAG00606 AF456425 AAL78672 AF456426 AAL78673 AK025764 BAB15235 AK056335 BAG51680 AK095773 AK297328 BAG59788 AK314480 BAG37084 AW103206 BC009478 AAH09478 BC013163 AAH13163 BI828039 BU620603 CD687300 HQ448015 ADQ32496 HY031019 HY052047 XM_005247539 XP_005247596 XM_011512912 XP_011511214 XM_011512913 XP_011511215 XM_011512914 XP_011511216 XM_011512915 XP_011511217 XM_011512916 XP_011511218 NM_001308101 NP_001295030 NM_020640 NP_065691
Function Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity). {ECO:0000250}.
Tissue Specificity Expressed in pancreas, kidney, placenta, brain and heart. Weakly or not expressed in liver, skeletal muscle and lung. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas. {ECO:0000269|PubMed:10777668}.

Dcun1D1 (3E1) - sc-81835 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Dcun1D1 (3E1): sc-81835. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing membrane and cytoplasmic localization.

Dcun1D1/2 (A-11) - sc-398218 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dcun1D1/2 (A-11): sc-398218. Western blot analysis of Dcun1D1/2 expression in TT (A), SCC-4 (B), HeLa (C), HEK293 (D) and U-937 (E) whole cell lysates.

Dcun1D1/2 (H-163) - sc-292704 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-DCUN1D1 antibody - ab57255 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DCUN1D1 antibody [EPR13492] - ab181233 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13492
All lanes : Anti-DCUN1D1 antibody [EPR13492] (ab181233) at 1/20000 dilutionLane 1 : A549 cell lysateLane 2 : HT29 cell lysateLane 3 : HepG2 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-DCUN1D1 / SCCRO Antibody (aa248-258) IHC-plus™ - LS-B9526 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-DCUN1D1 / SCCRO antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9526 concentration 5 ug/ml.

Anti-DCUN1D1 / SCCRO Antibody (aa1-90, clone 10B2674, Azide-free) - LS-C183550 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2674

Anti-DCUN1D1 / SCCRO Antibody - LS-C310096 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DCUN1D1 / SCCRO Antibody - LS-C310097 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DCUN1D1 / SCCRO Antibody (C-Terminus) - LS-C110701 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DCUN1D1 antibody LS-C110701 Western blot of PANC1 cell lysate.

Anti-DCUN1D1 / SCCRO Antibody (aa31-80) - LS-C40394 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DCUN1D1 antibody LS-C40394 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-DCUN1D1 / SCCRO Antibody (clone 4B5) - LS-C139521 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B5
DCUN1D1 monoclonal antibody (M02), clone 4B5. Western blot of DCUN1D1 expression in Raw 264.7.

DCUN1D1 Antibody (3D7) - H00054165-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D7
Western Blot: DCUN1D1 Antibody (3D7) [H00054165-M01] - DCUN1D1 monoclonal antibody (M01), clone 3D7. Analysis of DCUN1D1 expression in NIH/3T3.

DCUN1D1 Antibody - NBP1-56537 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DCUN1D1 Antibody - NBP1-85275 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DCUN1D1 Antibody (4B5) - H00054165-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B5
Western Blot: DCUN1D1 Antibody (4B5) [H00054165-M02] - DCUN1D1 monoclonal antibody (M02), clone 4B5. Analysis of DCUN1D1 expression in Raw 264.7.

DCUN1D1 Antibody - NBP1-52025 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

DCUN1D1 Antibody - NBP2-16117 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DCUN1D1 Antibody [NBP2-16117] - Sample (30 ug of whole cell lysate) A: A431 B: JurKat C: Raji 12% SDS PAGE gel, diluted at 1:1000.

DCUN1D1 Antibody - NBP2-16116 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DCUN1D1 Antibody [NBP2-16116] - Sample (30 ug of whole cell lysate) A: A431 B: JurKat C: Raji 12% SDS PAGE gel, diluted at 1:1000.

DCUN1D1 Antibody - H00054165-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DCUN1D1 Antibody [H00054165-B01] - analysis of DCUN1D1 expression in transfected 293T cell line by DCUN1D1 MaxPab polyclonal antibody (B01). Lane 1: DCUN1D1 transfected lysate (30.10 KDa). Lane 2: Non-transfected lysate.

DCUN1D1 Antibody - H00054165-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: DCUN1D1 Antibody [H00054165-A01] - DCUN1D1 polyclonal antibody (A01), Lot # 060524JCS1 Western Blot analysis of DCUN1D1 expression in Hela NE ( Cat # L013V3 ).

DCUN1D1 Antibody - H00054165-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

DCUN1D1 Antibody - H00054165-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SCRO Polyclonal Antibody - bs-6523R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-DCUN1D1, (N-terminal) antibody produced in mouse - SAB1405120 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B5
<B>Immunoblotting</B><BR/>Monoclonal Anti-DCUN1D1: <B>Cat. No. SAB1405120</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~30.1 kDa using PC~12 lysate.
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