AKR1C4

Gene Symbol	AKR1C4
Entrez Gene	1109
Alt Symbol	3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member C4
Other Description	3-alpha-HSD1|aldo-keto reductase family 1 member C4|chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4|dihydrodiol dehydrogenase isozyme DD4|type I 3-alpha-hydroxysteroid dehydrogenase
Swissprots	Q5T6A3 Q8WW84 Q9NS54 P17516
Accessions	AAB47003 BAA92893 BAB43901 CBX51394 EAW86450 P17516 AB031085 BAA92885 AB045829 BAA99542 AK314988 BC020744 AAH20744 D26125 BAA05122 DQ891424 ABM82350 DQ894598 ABM85524 M33375 AAA35658 S68287 AAD14010 XM_011519303 XP_011517605 NM_001818 NP_001809
Function	Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Subcellular Location	Cytoplasm.
Tissue Specificity	Liver specific. {ECO:0000269|PubMed:11158055, ECO:0000269|PubMed:7650035}.
Top Pathways	Primary bile acid biosynthesis, Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AKR1C4 / Chlordecone Reductase ELISA Kit (Sandwich ELISA) - LS-F10779 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Aldo-keto reductase family 1 member C4 (AKR1C4), Human, ELISA Kit - E01A1374 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 250-5000pg/ml

Aldo-keto reductase family 1 member C4, AKR1C4, Human, ELISA Kit - E2449h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

AKR1C4 (Human) IP-WB Antibody Pair - H00001109-PW1 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Aldo keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7212263 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7227396 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7247401 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7213618 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7201333 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7225143 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7212125 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7252317 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7204446 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7240624 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7235530 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Aldo-keto reductase family 1 member C4 (AKR1C4), ELISA Kit - MBS7211518 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) , ELISA Kit - MBS9329809 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.5ng/ml-16ng/ml.

Human Aldo-keto reductase family 1 member C4 ELISA Kit - abx251567 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Aldo-keto reductase family 1 member C4 ELISA Kit - EKE54171 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/mL Range 0.156-10 ng/mL

AKR1C4 - EKH4446 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

AKR1C4 ELISA Kit (Human) (OKEH01649) - OKEH01649 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.078 ng/mL Range 0.156 - 10 ng/mL

Custom Human AKR1C4 ELISA - ELH-AKR1C4-1 from RayBiotech Category ELISA Kit Prices $627.00, $1,128.60, $2,508.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human AKR1C4 ELISA Kit - E001323 from Biobool Category ELISA Kit Sensitivity 0.1 ng/mL.

Human Aldo-keto reductase family 1 member C4 ELISA Kit - EK4518 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Range 31.2-2000 pg/mL

anti-AKR1C4 antibody - ARG63964 from Arigo Biolaboratories Category ELISA Kit

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