AKR1C4

Gene Symbol	AKR1C4
Entrez Gene	1109
Alt Symbol	3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA
Species	Human
Gene Type	protein-coding
Description	aldo-keto reductase family 1, member C4
Other Description	3-alpha-HSD1\|aldo-keto reductase family 1 member C4\|chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4\|dihydrodiol dehydrogenase isozyme DD4\|type I 3-alpha-hydroxysteroid dehydrogenase
Swissprots	Q5T6A3 Q8WW84 Q9NS54 P17516
Accessions	AAB47003 BAA92893 BAB43901 CBX51394 EAW86450 P17516 AB031085 BAA92885 AB045829 BAA99542 AK314988 BC020744 AAH20744 D26125 BAA05122 DQ891424 ABM82350 DQ894598 ABM85524 M33375 AAA35658 S68287 AAD14010 XM_011519303 XP_011517605 NM_001818 NP_001809
Function	Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha- androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20- alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Subcellular Location	Cytoplasm.
Tissue Specificity	Liver specific. {ECO:0000269\|PubMed:11158055, ECO:0000269\|PubMed:7650035}.
Top Pathways	Primary bile acid biosynthesis, Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450

Human-AKR1C4-cDNA-Clone - DC04974 from Abgent, a WuXi AppTec company

Prices	$436.05
Sizes	10 µg
Species	Human
Accession	BC020744

AKR1C4 - MBS1276143 from MyBioSource

Prices	$175.00
Sizes	10ug plasmid + 200ul glycerol stock
Species	Human
Accession	BC020744

Human AKR1C4 ORF Clone(NM_001818.3) - CDCL153522 from Creative Biomart

Species	Human
Accession	NM_001818.3

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone in cloning vector - HG15307-G from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15307-ACG from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15307-NY from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15307-NF from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15307-ANG from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-His tag - HG15307-NH from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15307-CF from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15307-NM from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15307-CM from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-His tag - HG15307-CH from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15307-CY from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid - HG15307-UT from Sino Biological

Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15307-ANR from Sino Biological

Species	Human

Human AKR1C4 ORF Clone (BC020744) - CDCS410456 from Creative biogene

Species	Human
Accession	P17516

Human AKR1C4 ORF clone (BC020744) - CDCB157782 from Creative biogene

Species	Human

Human AKR1C4 Gene cDNA Clone - orb141735 from Biorbyt

Prices	$264.00
Sizes	10 μg
Species	Human

Human AKR1C4/3-alpha-HSD1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15307-ACR from Sino Biological

Species	Human

Human POLR3K Gene ORF cDNA clone expression plasmid, N-Flag tag - HG21758-NF from Sino Biological

Species	Human

Human POLR3K Gene ORF cDNA clone expression plasmid, N-His tag - HG21758-NH from Sino Biological

Species	Human

Human POLR3K Gene ORF cDNA clone expression plasmid, N-Myc tag - HG21758-NM from Sino Biological

Species	Human

Human POLR3K Gene ORF cDNA clone expression plasmid, N-HA tag - HG21758-NY from Sino Biological

Species	Human

Human POLR3K Gene ORF cDNA clone in cloning vector - HG21758-U from Sino Biological

Species	Human

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