RIC3

Gene Symbol RIC3
Entrez Gene 79608
Alt Symbol AYST720, PRO1385
Species Human
Gene Type protein-coding
Description RIC3 acetylcholine receptor chaperone
Other Description protein RIC-3|resistance to inhibitors of cholinesterase 3 homolog|resistant to inhibitor of cholinesterase 3
Swissprots B0B1U0 Q8TBJ9 Q7Z5B3 Q9HAH8 B2RD25 D3DQU5 Q6UX78 Q86T94 Q7Z5B4
Accessions CAE90186 EAW68627 EAW68628 EAW68629 EAW68630 EAW68631 Q7Z5B4 AK021670 BAB13871 AK022297 AK128611 AK293933 BAH11630 AK296505 BAH12376 AK315379 BAG37772 AL390131 AL832601 CAD89943 AM422214 CAM12309 AY326435 AAP92162 AY326436 AAP92163 AY358475 AAQ88839 BC022455 AAH22455 BQ941375 BX647514 CB850751 DA186330 DC420812 DQ347704 DQ347705 XM_006718317 XP_006718380 XM_006718318 XP_006718381 XM_006718321 XP_006718384 XM_011520366 XP_011518668 XR_428848 XR_428851 XR_930896 XR_930897 XR_930898 XR_930899 XR_930900 XR_930901 XR_930902 XR_930903 XR_930904 XR_930905 XR_930906 NM_001135109 NP_001128581 NM_001206671 NP_001193600 NM_001206672 NP_001193601 NM_024557 NP_078833 NR_045405
Function Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:15504725, ECO:0000269|PubMed:15809299, ECO:0000269|PubMed:15927954, ECO:0000269|PubMed:16120769, ECO:0000269|PubMed:17609200, ECO:0000269|PubMed:18691158}.
Subcellular Location Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland. Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:17640815, ECO:0000269|PubMed:18691158}.

resistance to inhibitors of cholinesterase 3 homolog (C. elegans) , ELISA Kit - MBS9343016 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human RIC3 ELISA Kit - E033227 from Biobool

Category ELISA Kit
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