RIC3

Gene Symbol RIC3
Entrez Gene 79608
Alt Symbol AYST720, PRO1385
Species Human
Gene Type protein-coding
Description RIC3 acetylcholine receptor chaperone
Other Description protein RIC-3|resistance to inhibitors of cholinesterase 3 homolog|resistant to inhibitor of cholinesterase 3
Swissprots B0B1U0 Q8TBJ9 Q7Z5B3 Q9HAH8 B2RD25 D3DQU5 Q6UX78 Q86T94 Q7Z5B4
Accessions CAE90186 EAW68627 EAW68628 EAW68629 EAW68630 EAW68631 Q7Z5B4 AK021670 BAB13871 AK022297 AK128611 AK293933 BAH11630 AK296505 BAH12376 AK315379 BAG37772 AL390131 AL832601 CAD89943 AM422214 CAM12309 AY326435 AAP92162 AY326436 AAP92163 AY358475 AAQ88839 BC022455 AAH22455 BQ941375 BX647514 CB850751 DA186330 DC420812 DQ347704 DQ347705 XM_006718317 XP_006718380 XM_006718318 XP_006718381 XM_006718321 XP_006718384 XM_011520366 XP_011518668 XR_428848 XR_428851 XR_930896 XR_930897 XR_930898 XR_930899 XR_930900 XR_930901 XR_930902 XR_930903 XR_930904 XR_930905 XR_930906 NM_001135109 NP_001128581 NM_001206671 NP_001193600 NM_001206672 NP_001193601 NM_024557 NP_078833 NR_045405
Function Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:15504725, ECO:0000269|PubMed:15809299, ECO:0000269|PubMed:15927954, ECO:0000269|PubMed:16120769, ECO:0000269|PubMed:17609200, ECO:0000269|PubMed:18691158}.
Subcellular Location Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland. Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:17640815, ECO:0000269|PubMed:18691158}.

Human RIC3 full length protein - ab164047 from Abcam

Category Protein
Source Wheat germ
Species Human
ab164047 on a 12.5% SDS-PAGE stained with Coomassie Blue.

RIC3 Antibody Blocking Peptide - LS-E1886 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human RIC3 Protein - H00079608-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

RIC3-Antibody-C-term-Blocking-peptide - BP12721b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

RIC3 - H00079608-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

RIC3 - H00079608-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

RIC3 fusion protein - ag3479 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Protein RIC-3(RIC3) - CSB-YP800217HU CSB-EP800217HU CSB-BP800217HU CSB-MP800217HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RIC3 Recombinant Protein Antigen - NBP2-38058PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

RIC3 Peptide, Human - M34GP13295H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

RIC3 fusion protein - Ag26740 from Proteintech Group

Category Protein
Source E. coli -derived, PGEX-4T
Species Human

Protein RIC-3 (RIC3), Recombinant Protein - MBS1280844 from MyBioSource

Category Protein
Prices $1,000.00, $1,000.00, $1,235.00, $1,235.00, $1,540.00, $1,540.00, $2,005.00, $2,005.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

RIC3 fusion protein - Ag26854 from Proteintech Group

Category Protein
Source E. coli -derived, PET28a
Species Human
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