RIC3

Gene Symbol	RIC3
Entrez Gene	79608
Alt Symbol	AYST720, PRO1385
Species	Human
Gene Type	protein-coding
Description	RIC3 acetylcholine receptor chaperone
Other Description	protein RIC-3|resistance to inhibitors of cholinesterase 3 homolog|resistant to inhibitor of cholinesterase 3
Swissprots	B0B1U0 Q8TBJ9 Q7Z5B3 Q9HAH8 B2RD25 D3DQU5 Q6UX78 Q86T94 Q7Z5B4
Accessions	CAE90186 EAW68627 EAW68628 EAW68629 EAW68630 EAW68631 Q7Z5B4 AK021670 BAB13871 AK022297 AK128611 AK293933 BAH11630 AK296505 BAH12376 AK315379 BAG37772 AL390131 AL832601 CAD89943 AM422214 CAM12309 AY326435 AAP92162 AY326436 AAP92163 AY358475 AAQ88839 BC022455 AAH22455 BQ941375 BX647514 CB850751 DA186330 DC420812 DQ347704 DQ347705 XM_006718317 XP_006718380 XM_006718318 XP_006718381 XM_006718321 XP_006718384 XM_011520366 XP_011518668 XR_428848 XR_428851 XR_930896 XR_930897 XR_930898 XR_930899 XR_930900 XR_930901 XR_930902 XR_930903 XR_930904 XR_930905 XR_930906 NM_001135109 NP_001128581 NM_001206671 NP_001193600 NM_001206672 NP_001193601 NM_024557 NP_078833 NR_045405
Function	Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:15504725, ECO:0000269|PubMed:15809299, ECO:0000269|PubMed:15927954, ECO:0000269|PubMed:16120769, ECO:0000269|PubMed:17609200, ECO:0000269|PubMed:18691158}.
Subcellular Location	Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity	Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland. Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:17640815, ECO:0000269|PubMed:18691158}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RIC3 Gene cDNA Clone - orb145056 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-RIC3-cDNA-Clone - DC05259 from Abgent, a WuXi AppTec company Prices $498.15 Sizes 10 µg Species Human Accession BC022455

RIC3 - MBS1266475 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022455

Human RIC3 Gene ORF cDNA clone in cloning vector - HG13376-G from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13376-NM from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13376-CF from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13376-CM from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13376-ANG from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-His tag - HG13376-NH from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13376-ACR from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13376-ANR from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-His tag - HG13376-CH from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13376-ACG from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13376-CY from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid - HG13376-UT from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13376-NY from Sino Biological Species Human

Human RIC3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13376-NF from Sino Biological Species Human

Human RIC3 ORF Clone(NM_001135109.2) - CDCR350233 from Creative biogene Species Human

human RIC3 ORF clone (NM_001206671.2) - CDCH073852 from Creative biogene Species Human

human RIC3 ORF clone (NM_001206672.2) - CDCH073854 from Creative biogene Species Human

Human RIC3 ORF Clone (BC022455) - CDCS408055 from Creative biogene Species Human Accession Q7Z5B4

Human RIC3 ORF clone (BC022455) - CDCB159796 from Creative biogene Species Human

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