RIC3

Gene Symbol RIC3
Entrez Gene 79608
Alt Symbol AYST720, PRO1385
Species Human
Gene Type protein-coding
Description RIC3 acetylcholine receptor chaperone
Other Description protein RIC-3|resistance to inhibitors of cholinesterase 3 homolog|resistant to inhibitor of cholinesterase 3
Swissprots B0B1U0 Q8TBJ9 Q7Z5B3 Q9HAH8 B2RD25 D3DQU5 Q6UX78 Q86T94 Q7Z5B4
Accessions CAE90186 EAW68627 EAW68628 EAW68629 EAW68630 EAW68631 Q7Z5B4 AK021670 BAB13871 AK022297 AK128611 AK293933 BAH11630 AK296505 BAH12376 AK315379 BAG37772 AL390131 AL832601 CAD89943 AM422214 CAM12309 AY326435 AAP92162 AY326436 AAP92163 AY358475 AAQ88839 BC022455 AAH22455 BQ941375 BX647514 CB850751 DA186330 DC420812 DQ347704 DQ347705 XM_006718317 XP_006718380 XM_006718318 XP_006718381 XM_006718321 XP_006718384 XM_011520366 XP_011518668 XR_428848 XR_428851 XR_930896 XR_930897 XR_930898 XR_930899 XR_930900 XR_930901 XR_930902 XR_930903 XR_930904 XR_930905 XR_930906 NM_001135109 NP_001128581 NM_001206671 NP_001193600 NM_001206672 NP_001193601 NM_024557 NP_078833 NR_045405
Function Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface. May also promote functional expression of homomeric serotoninergic 5- HT3 receptors, and of heteromeric acetylcholine receptors alpha- 3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:15504725, ECO:0000269|PubMed:15809299, ECO:0000269|PubMed:15927954, ECO:0000269|PubMed:16120769, ECO:0000269|PubMed:17609200, ECO:0000269|PubMed:18691158}.
Subcellular Location Isoform 1: Endoplasmic reticulum membrane; Single-pass membrane protein.
Tissue Specificity Broadly expressed, with high levels in muscle, brain, heart, pancreas and testis. In the central nervous system, highest levels are detected in the cerebellum and pituitary gland. Over-expressed in brains from patients with bipolar disease or schizophrenia. Isoform 5 is predominantly expressed in the brain. {ECO:0000269|PubMed:12821669, ECO:0000269|PubMed:17640815, ECO:0000269|PubMed:18691158}.

RIC-3 CRISPR/Cas9 KO Plasmid (h) - sc-405366 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 HDR Plasmid (h) - sc-405366-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 Double Nickase Plasmid (h) - sc-405366-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 Double Nickase Plasmid (h2) - sc-405366-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 CRISPR Activation Plasmid (h) - sc-405366-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 CRISPR Activation Plasmid (h2) - sc-405366-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 Lentiviral Activation Particles (h) - sc-405366-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 Lentiviral Activation Particles (h2) - sc-405366-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RIC-3 siRNA (h) - sc-72301 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RIC-3 shRNA Plasmid (h) - sc-72301-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RIC-3 shRNA (h) Lentiviral Particles - sc-72301-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU145501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18272 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18272 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10287 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10287

RIC3 siRNA (Human) - CRJ2423 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RIC3 - MBS8231262 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RIC3 (NM_024557.4) - SHH395660 from Creative biogene

Category siRNA
Species Reactivities Human

Human RIC3 siRNA - orb272924 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RIC3 shRNA Plasmid (Human) - CHJ2423 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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